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6L6R
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BU of 6l6r by Molmil
Crystal structure of LRP6 E1E2-SOST complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Choi, H.-J, Kim, J.
登録日2019-10-29
公開日2020-10-28
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains.
Nat Commun, 11, 2020
3HWC
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BU of 3hwc by Molmil
Crystal Structure of Chlorophenol 4-Monooxygenase (TftD) of Burkholderia cepacia AC1100
分子名称: Chlorophenol-4-monooxygenase component 2
著者Ballinger, J.W, Kang, C.H.
登録日2009-06-17
公開日2009-11-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Characterization of chlorophenol 4-monooxygenase (TftD) and NADH:FAD oxidoreductase (TftC) of Burkholderia cepacia AC1100.
J.Biol.Chem., 285, 2010
3K87
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BU of 3k87 by Molmil
Crystal structure of NADH:FAD oxidoreductase (TftC) - FAD complex
分子名称: Chlorophenol-4-monooxygenase component 1, FLAVIN-ADENINE DINUCLEOTIDE
著者Kang, C.H, Webb, B.N.
登録日2009-10-13
公開日2009-11-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterization of chlorophenol 4-monooxygenase (TftD) and NADH:FAD oxidoreductase (TftC) of Burkholderia cepacia AC1100.
J.Biol.Chem., 285, 2010
5TQM
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BU of 5tqm by Molmil
Cinnamoyl-CoA Reductase 1 from Sorghum bicolor in complex with NADP+
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Cinnamoyl-CoA Reductase, GLYCEROL, ...
著者Sattler, S.A, Kang, C.H.
登録日2016-10-24
公開日2017-04-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and Biochemical Characterization of Cinnamoyl-CoA Reductases.
Plant Physiol., 173, 2017
5KHT
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BU of 5kht by Molmil
Crystal structure of the N-terminal fragment of tropomyosin isoform Tpm1.1 at 1.5 A resolution
分子名称: DI(HYDROXYETHYL)ETHER, Tropomyosin alpha-1 chain,General control protein GCN4
著者Kostyukova, A.S, Krieger, I, Yoon, Y.-H, Tolkatchev, D, Samatey, F.A.
登録日2016-06-15
公開日2017-06-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.4964 Å)
主引用文献Structural destabilization of tropomyosin induced by the cardiomyopathy-linked mutation R21H.
Protein Sci., 27, 2018
7F0S
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BU of 7f0s by Molmil
A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically 1dynamic RNA-dependent RNA polymerase
分子名称: RNA-directed RNA polymerase nsP4
著者Tan, Y.B, Luo, D.
登録日2021-06-06
公開日2022-02-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.
Nucleic Acids Res., 50, 2022
6L4Z
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BU of 6l4z by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 6
分子名称: 4-(hydroxymethyl)benzoic acid, Genome polyprotein
著者Quek, J.P.
登録日2019-10-21
公開日2020-07-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease.
Antiviral Res., 175, 2020
6L50
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BU of 6l50 by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 16
分子名称: 2-sulfanylidene-1,3-thiazolidin-4-one, NS3 protease, Serine protease subunit NS2B
著者Quek, J.P.
登録日2019-10-21
公開日2020-07-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease.
Antiviral Res., 175, 2020
4PPI
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BU of 4ppi by Molmil
Crystal structure of Bcl-xL hexamer
分子名称: Bcl-2-like protein 1, GLYCEROL
著者Sreekanth, R, Yoon, H.S.
登録日2014-02-27
公開日2015-03-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.851 Å)
主引用文献Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport
Sci Rep, 5, 2015
3AFP
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BU of 3afp by Molmil
Crystal structure of the single-stranded DNA binding protein from Mycobacterium leprae (Form I)
分子名称: CADMIUM ION, GLYCEROL, Single-stranded DNA-binding protein
著者Kaushal, P.S, Singh, P, Sharma, A, Muniyappa, K, Vijayan, M.
登録日2010-03-10
公開日2010-10-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献X-ray and molecular-dynamics studies on Mycobacterium leprae single-stranded DNA-binding protein and comparison with other eubacterial SSB structures
Acta Crystallogr.,Sect.D, 66, 2010
3AFQ
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BU of 3afq by Molmil
Crystal structure of the single-stranded DNA binding protein from Mycobacterium leprae (Form II)
分子名称: Single-stranded DNA-binding protein
著者Kaushal, P.S, Singh, P, Sharma, A, Muniyappa, K, Vijayan, M.
登録日2010-03-10
公開日2010-10-06
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献X-ray and molecular-dynamics studies on Mycobacterium leprae single-stranded DNA-binding protein and comparison with other eubacterial SSB structures
Acta Crystallogr.,Sect.D, 66, 2010
5DQE
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BU of 5dqe by Molmil
Crystal structure of human transcription factor TEAD2 in complex with bromo-fenamic acid
分子名称: 2-[(3-bromophenyl)amino]benzoic acid, Transcriptional enhancer factor TEF-4
著者Han, X, Luo, X.
登録日2015-09-14
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.183 Å)
主引用文献Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.
Structure, 23, 2015
5DQ8
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BU of 5dq8 by Molmil
Crystal structure of human transcription factor TEAD2 in complex with flufenamic acid
分子名称: 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, Transcriptional enhancer factor TEF-4
著者Han, X, Luo, X.
登録日2015-09-14
公開日2015-11-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.305 Å)
主引用文献Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy.
Structure, 23, 2015
5GJ4
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BU of 5gj4 by Molmil
Structure of NS2B-NS3 Protease from Zika Virus caught after self-cleavage
分子名称: CHLORIDE ION, Serine protease NS3, Serine protease subunit NS2B
著者Phoo, W.W, Li, Y.
登録日2016-06-27
公開日2016-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.839 Å)
主引用文献Structure of the NS2B-NS3 protease from Zika virus after self-cleavage.
Nat Commun, 7, 2016
5H4I
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BU of 5h4i by Molmil
Unlinked NS2B-NS3 Protease from Zika Virus in complex with a compound fragment
分子名称: ACETATE ION, NS2B cofactor, NS3 protease, ...
著者Zhang, Z.Z, Li, Y.
登録日2016-10-31
公開日2016-12-14
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Crystal structure of unlinked NS2B-NS3 protease from Zika virus
Science, 354, 2016
5GPI
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BU of 5gpi by Molmil
Crystal Structures of Unlinked NS2B-NS3 Protease from Zika Virus and Its Complex with a Reverse Peptide Inhibitor
分子名称: NS2B cofactor, NS3 protease
著者Phoo, W.W, Zhang, Z.Z.
登録日2016-08-02
公開日2016-12-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.578 Å)
主引用文献Crystal structure of unlinked NS2B-NS3 protease from Zika virus
Science, 354, 2016
5H6V
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BU of 5h6v by Molmil
Structure of Zika virus protease in complex with a dipeptide inhibitor
分子名称: (S)-2-acetamido-6-amino-N-((S)-5-guanidino-1-oxopentan-2-yl)hexanamide, Genome polyprotein
著者Zhang, Z, Chen, M.
登録日2016-11-15
公開日2017-06-14
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.422 Å)
主引用文献Structural Dynamics of Zika Virus NS2B-NS3 Protease Binding to Dipeptide Inhibitors
Structure, 25, 2017
5YOF
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BU of 5yof by Molmil
Crystal structure of zika virus NS3 protease in complex with a dipeptide inhibitor
分子名称: (S)-2-acetamido-6-amino-N-((S)-5-guanidino-1-oxopentan-2-yl)hexanamide, NS2B cofactor, NS3 Protease
著者Phoo, W.W, Zhang, Z.Z.
登録日2017-10-27
公開日2018-03-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
Structure, 26, 2018
5YOD
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BU of 5yod by Molmil
Crystal structure of zika virus NS3 protease in complex with a small molecule inhibitor
分子名称: BENZOIC ACID, NS2B cofactor, NS3 protease
著者Phoo, W.W, Zhang, Z.Z.
登録日2017-10-27
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
Structure, 26, 2018
7VW5
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BU of 7vw5 by Molmil
Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold
分子名称: MAGNESIUM ION, RNA-directed RNA polymerase nsP4
著者Tan, Y.B, Luo, D.
登録日2021-11-09
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.
Nucleic Acids Res., 50, 2022
7VB4
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BU of 7vb4 by Molmil
A crystal structure of alphavirus nonstructural protein 4 (nsP4) reveals an intrinsically dynamic RNA-dependent RNA polymerase
分子名称: GLYCEROL, MAGNESIUM ION, RNA-directed RNA polymerase nsP4
著者Tan, Y.B, Luo, D.
登録日2021-08-30
公開日2022-02-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.
Nucleic Acids Res., 50, 2022
7F8G
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BU of 7f8g by Molmil
Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase
分子名称: 3-phenoxy-~{N}-[(~{E})-(5-pyrimidin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide, Eyes absent homolog 2
著者Anantharajan, J, Baburajendran, N.
登録日2021-07-02
公開日2021-12-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.491 Å)
主引用文献Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase.
Protein Sci., 31, 2022
7F8H
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BU of 7f8h by Molmil
Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase
分子名称: 3-fluoranyl-~{N}-[(~{E})-(5-pyridin-2-ylsulfanylfuran-2-yl)methylideneamino]benzamide, Eyes absent homolog 2
著者Anantharajan, J, Baburajendran, N.
登録日2021-07-02
公開日2021-12-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase.
Protein Sci., 31, 2022
2MHF
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BU of 2mhf by Molmil
Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel
分子名称: Uncharacterized protein
著者Li, Q, Ng, H.
登録日2013-11-21
公開日2014-04-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the cyclic-nucleotide binding homology domain of a KCNH channel.
J.Struct.Biol., 186, 2014
2LAV
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BU of 2lav by Molmil
NMR solution structure of human Vaccinia-Related Kinase 1
分子名称: Vaccinia-related kinase 1
著者Shin, J, Yoon, H.S.
登録日2011-03-21
公開日2011-05-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of Human Vaccinia-related Kinase 1 (VRK1) Reveals the C-terminal Tail Essential for Its Structural Stability and Autocatalytic Activity.
J.Biol.Chem., 286, 2011

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件を2025-07-09に公開中

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