5KHT
Crystal structure of the N-terminal fragment of tropomyosin isoform Tpm1.1 at 1.5 A resolution
Summary for 5KHT
Entry DOI | 10.2210/pdb5kht/pdb |
Descriptor | Tropomyosin alpha-1 chain,General control protein GCN4, DI(HYDROXYETHYL)ETHER (3 entities in total) |
Functional Keywords | tropomyosin, coiled coil, actin-binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 22237.67 |
Authors | Kostyukova, A.S.,Krieger, I.,Yoon, Y.-H.,Tolkatchev, D.,Samatey, F.A. (deposition date: 2016-06-15, release date: 2017-06-21, Last modification date: 2024-04-03) |
Primary citation | Ly, T.,Krieger, I.,Tolkatchev, D.,Krone, C.,Moural, T.,Samatey, F.A.,Kang, C.,Kostyukova, A.S. Structural destabilization of tropomyosin induced by the cardiomyopathy-linked mutation R21H. Protein Sci., 27:498-508, 2018 Cited by PubMed: 29105867DOI: 10.1002/pro.3341 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4964 Å) |
Structure validation
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