5YOD
Crystal structure of zika virus NS3 protease in complex with a small molecule inhibitor
Summary for 5YOD
Entry DOI | 10.2210/pdb5yod/pdb |
Descriptor | NS2B cofactor, NS3 protease, BENZOIC ACID, ... (4 entities in total) |
Functional Keywords | non-structural protein 3, serine protease, zika viral protease, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Zika virus More |
Total number of polymer chains | 8 |
Total formula weight | 100036.13 |
Authors | Phoo, W.W.,Zhang, Z.Z. (deposition date: 2017-10-27, release date: 2018-03-21, Last modification date: 2023-11-22) |
Primary citation | Li, Y.,Zhang, Z.,Phoo, W.W.,Loh, Y.R.,Li, R.,Yang, H.Y.,Jansson, A.E.,Hill, J.,Keller, T.H.,Nacro, K.,Luo, D.,Kang, C. Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor Structure, 26:555-564.e3, 2018 Cited by PubMed: 29526431DOI: 10.1016/j.str.2018.02.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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