7VW5

Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold

Summary for 7VW5

• Entry DOI: 10.2210/pdb7vw5/pdb
• Related: 7F0S 7VB4
• Descriptor: RNA-directed RNA polymerase nsP4, MAGNESIUM ION (3 entities in total)
• Functional Keywords: rna dependent rna polymerase, rna directed rna polymerase, rdrp, alphavirus, nsp4, nonstructural protein 4, transferase
• Biological source: Sindbis virus
• Total number of polymer chains: 2
• Total formula weight: 116802.23

Authors

Tan, Y.B.,Luo, D. (deposition date: 2021-11-09, release date: 2022-02-16, Last modification date: 2023-11-29)

• Primary citation: Tan, Y.B.,Lello, L.S.,Liu, X.,Law, Y.S.,Kang, C.,Lescar, J.,Zheng, J.,Merits, A.,Luo, D.; Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.; Nucleic Acids Res., 50:1000-1016, 2022; PubMed: 35037043; DOI: 10.1093/nar/gkab1302

Experimental method

X-RAY DIFFRACTION (2.3 Å)