7VW5
Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RNA-directed RNA polymerase nsP4 | polymer | 520 | 58376.8 | 2 | UniProt (P03317) Pfam (PF00978) | Sindbis virus | Non-structural protein 4,nsP4 |
| 2 | C, D (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 346 | Chemie (HOH) |
Sequence modifications
A, B: 91 - 610 (UniProt: P03317)
| PDB | External Database | Details |
|---|---|---|
| Ser 164 | Cys 2067 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116753.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 116802.2 |
