5H6V
Structure of Zika virus protease in complex with a dipeptide inhibitor
Summary for 5H6V
Entry DOI | 10.2210/pdb5h6v/pdb |
NMR Information | BMRB: 26933 |
Descriptor | Genome polyprotein, (S)-2-acetamido-6-amino-N-((S)-5-guanidino-1-oxopentan-2-yl)hexanamide, ... (4 entities in total) |
Functional Keywords | serine protease, non-structural protein 3, viral protein-inhibitor complex, viral protein/inhibitor |
Biological source | Zika virus (ZIKV) More |
Total number of polymer chains | 2 |
Total formula weight | 25088.29 |
Authors | |
Primary citation | Li, Y.,Zhang, Z.,Phoo, W.W.,Loh, Y.R.,Wang, W.,Liu, S.,Chen, M.W.,Hung, A.W.,Keller, T.H.,Luo, D.,Kang, C. Structural Dynamics of Zika Virus NS2B-NS3 Protease Binding to Dipeptide Inhibitors Structure, 25:1242-1250.e3, 2017 Cited by PubMed: 28689970DOI: 10.1016/j.str.2017.06.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.422 Å) |
Structure validation
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