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4R7L
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BU of 4r7l by Molmil
Structure of Human Leukotriene A4 Hydrolase in complex with inhibitor H1
分子名称: ACETATE ION, GLYCEROL, IMIDAZOLE, ...
著者Ouyang, P, Cui, K, Lu, W, Huang, J.
登録日2014-08-27
公開日2015-11-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Human Leukotriene A4 Hydrolase in complex with SAHA
To be Published
4E9A
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BU of 4e9a by Molmil
Structure of Peptide Deformylase form Helicobacter Pylori in complex with inhibitor
分子名称: 2-phenylethyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COBALT (II) ION, ...
著者Cui, K, Zhu, L, Lu, W, Huang, J.
登録日2012-03-20
公開日2013-04-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.662 Å)
主引用文献Identification of Novel Peptide Deformylase Inhibitors from Natural Products
To be Published
4CC6
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BU of 4cc6 by Molmil
Fragment-Based Discovery of 6 Azaindazoles As Inhibitors of Bacterial DNA Ligase
分子名称: 2-{[2-(1H-pyrazolo[3,4-c]pyridin-3-yl)-6-(trifluoromethyl)pyridin-4-yl]amino}ethanol, DNA LIGASE, SULFATE ION
著者Howard, S, Amin, N, Benowitz, A.B, Chiarparin, E, Cui, H, Deng, X, Heightman, T.D, Holmes, D.J, Hopkins, A, Huang, J, Jin, Q, Kreatsoulas, C, Martin, A.C.L, Massey, F, McCloskey, L, Mortenson, P.N, Pathuri, P, Tisi, D, Williams, P.A.
登録日2013-10-18
公開日2014-06-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Fragment-Based Discovery of 6-Azaindazoles as Inhibitors of Bacterial DNA Ligase.
Acs Med.Chem.Lett., 4, 2013
4CC5
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BU of 4cc5 by Molmil
Fragment-Based Discovery of 6 Azaindazoles As Inhibitors of Bacterial DNA Ligase
分子名称: 2-chloranyl-6-(1H-1,2,4-triazol-3-yl)pyrazine, DNA LIGASE, SULFATE ION
著者Howard, S, Amin, N, Benowitz, A.B, Chiarparin, E, Cui, H, Deng, X, Heightman, T.D, Holmes, D.J, Hopkins, A, Huang, J, Jin, Q, Kreatsoulas, C, Martin, A.C.L, Massey, F, McCloskey, L, Mortenson, P.N, Pathuri, P, Tisi, D, Williams, P.A.
登録日2013-10-18
公開日2014-06-18
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Fragment-Based Discovery of 6-Azaindazoles as Inhibitors of Bacterial DNA Ligase.
Acs Med.Chem.Lett., 4, 2013
4E9B
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BU of 4e9b by Molmil
Structure of Peptide Deformylase form Helicobacter Pylori in complex with actinonin
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ACTINONIN, COBALT (II) ION, ...
著者Cui, K, Zhu, L, Lu, W, Huang, J.
登録日2012-03-20
公開日2013-04-24
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Identification of Novel Peptide Deformylase Inhibitors from Natural Products
To be Published
1DT0
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BU of 1dt0 by Molmil
CLONING, SEQUENCE, AND CRYSTALLOGRAPHIC STRUCTURE OF RECOMBINANT IRON SUPEROXIDE DISMUTASE FROM PSEUDOMONAS OVALIS
分子名称: FE (III) ION, SUPEROXIDE DISMUTASE
著者Bond, C.J, Huang, J, Hajduk, R, Flick, K, Heath, P, Stoddard, B.L.
登録日2000-01-10
公開日2000-12-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Cloning, sequence and crystallographic structure of recombinant iron superoxide dismutase from Pseudomonas ovalis.
Acta Crystallogr.,Sect.D, 56, 2000
1EMS
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BU of 1ems by Molmil
CRYSTAL STRUCTURE OF THE C. ELEGANS NITFHIT PROTEIN
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ETHYL MERCURY ION, NIT-FRAGILE HISTIDINE TRIAD FUSION PROTEIN, ...
著者Pace, H.C, Hodawadekar, S.C, Draganescu, A, Huang, J, Bieganowski, P, Pekarsky, Y, Croce, C.M, Brenner, C.
登録日2000-03-17
公開日2000-07-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers.
Curr.Biol., 10, 2000
4KN8
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BU of 4kn8 by Molmil
Crystal structure of Bs-TpNPPase
分子名称: Thermostable NPPase
著者Guo, Z, Wang, F, Huang, J, Gong, W, Ji, C.
登録日2013-05-09
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献Crystal Structure of Thermostable p-nitrophenylphosphatase from Bacillus Stearothermophilus (Bs-TpNPPase)
PROTEIN PEPT.LETT., 21, 2014
2IEL
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BU of 2iel by Molmil
CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus
分子名称: Hypothetical Protein TT0030
著者Zhu, J, Huang, J, Stepanyuk, G, Chen, L, Chang, J, Zhao, M, Xu, H, Liu, Z.J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2006-09-19
公開日2006-11-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献CRYSTAL STRUCTURE OF TT0030 from Thermus Thermophilus AT 1.6 ANGSTROMS RESOLUTION
To be Published
3TYH
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BU of 3tyh by Molmil
Crystal structure of oxo-cupper clusters binding to ferric binding protein from Neisseria gonorrhoeae
分子名称: COPPER (II) ION, FbpA protein
著者Chen, W.J, Wang, H.F, Zhou, C.J, Ye, D.R, Huang, J, Tan, X.S, Zhong, W.Q.
登録日2011-09-26
公開日2012-09-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of oxo-cupper clusters binding to ferric binding protein from Neisseria gonorrhoeae
To be Published
2JTK
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BU of 2jtk by Molmil
A functional domain of a Wnt signal protein
分子名称: Dickkopf-related protein 2
著者Chen, L, Shao, Y, Huang, J, Zheng, J.
登録日2007-08-02
公開日2008-07-08
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献Structural insight into the mechanisms of wnt signaling antagonism by dkk
J.Biol.Chem., 283, 2008
5Z2S
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BU of 5z2s by Molmil
Crystal structure of DUX4-HD2 domain
分子名称: Double homeobox protein 4
著者Dong, X, Zhang, W, Wu, H, Huang, J, Zhang, M, Wang, P, Zhang, H, Chen, Z, Chen, S, Meng, G.
登録日2018-01-03
公開日2018-04-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
5Z2T
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BU of 5z2t by Molmil
Crystal structure of DNA-bound DUX4-HD2
分子名称: 5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*TP*T)-3', 5'-D(P*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3', Double homeobox protein 4
著者Dong, X, Zhang, W, Wu, H, Huang, J, Zhang, M, Wang, P, Zhang, H, Chen, Z, Chen, S, Meng, G.
登録日2018-01-04
公開日2018-04-04
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
7DW5
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BU of 7dw5 by Molmil
Crystal structure of DUX4 HD1-HD2 domain complexed with ERG sites
分子名称: BROMIDE ION, DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3'), Double homeobox protein 4-like protein 2
著者Zhang, H, Cheng, N, Li, Z, Zhang, W, Dong, X, Huang, J, Meng, G.
登録日2021-01-15
公開日2021-11-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia.
Cancer Commun (Lond), 41, 2021
7Y7Y
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BU of 7y7y by Molmil
Cryo-EM structure of human GABA transporter GAT1 bound with nipecotic acid in NaCl solution in an inward-occluded state at 2.4 angstrom
分子名称: (3R)-piperidine-3-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Zhu, A, Huang, J, Kong, F, Tan, J, Lei, J, Yuan, Y, Yan, C.
登録日2022-06-22
公開日2023-04-26
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Molecular basis for substrate recognition and transport of human GABA transporter GAT1.
Nat.Struct.Mol.Biol., 30, 2023
7Y7V
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BU of 7y7v by Molmil
Cryo-EM structure of human apo GABA transporter GAT1 in an inward-open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Sodium- and chloride-dependent GABA transporter 1
著者Zhu, A, Huang, J, Kong, F, Tan, J, Lei, J, Yuan, Y, Yan, C.
登録日2022-06-22
公開日2023-04-26
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Molecular basis for substrate recognition and transport of human GABA transporter GAT1.
Nat.Struct.Mol.Biol., 30, 2023
7Y7Z
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BU of 7y7z by Molmil
Cryo-EM structure of human GABA transporter GAT1 bound with tiagabine in NaCl solution in an inward-open state at 3.2 angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Sodium- and chloride-dependent GABA transporter 1, ...
著者Zhu, A, Huang, J, Kong, F, Tan, J, Lei, J, Yuan, Y, Yan, C.
登録日2022-06-22
公開日2023-04-26
最終更新日2023-11-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular basis for substrate recognition and transport of human GABA transporter GAT1.
Nat.Struct.Mol.Biol., 30, 2023
7Y7W
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BU of 7y7w by Molmil
Cryo-EM structure of human GABA transporter GAT1 bound with GABA in NaCl solution in an inward-occluded state at 2.4 angstrom
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GAMMA-AMINO-BUTANOIC ACID, ...
著者Zhu, A, Huang, J, Kong, F, Tan, J, Lei, J, Yuan, Y, Yan, C.
登録日2022-06-22
公開日2023-04-26
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Molecular basis for substrate recognition and transport of human GABA transporter GAT1.
Nat.Struct.Mol.Biol., 30, 2023
7JJO
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BU of 7jjo by Molmil
Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound Beta1-Adrenergic Receptor
分子名称: Beta1-Adrenergic Receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者Su, M, Zhu, L, Zhang, Y, Paknejad, N, Dey, R, Huang, J, Lee, M.Y, Williams, D, Jordan, K.D, Eng, E.T, Ernst, O.P, Meyerson, J.R, Hite, R.K, Walz, T, Liu, W, Huang, X.Y.
登録日2020-07-27
公開日2020-09-02
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound beta 1 -Adrenergic Receptor.
Mol.Cell, 80, 2020
6J3N
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BU of 6j3n by Molmil
RORgammat LBD complexed with Ursonic Acid and SRC2.2
分子名称: (5beta)-3-oxours-12-en-28-oic acid, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, Nuclear receptor ROR-gamma
著者Liu, Z.H, Huang, J, Tang, Y.
登録日2019-01-05
公開日2020-01-15
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structure of human RORgammat LBD with SCR2.2 at 1.99 Angstroms resolution
To Be Published
6J99
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BU of 6j99 by Molmil
Cryo-EM structure of human DOT1L in complex with an H2B-monoubiquitinated nucleosome
分子名称: DNA (144-MER), DNA (145-MER), Histone H2A, ...
著者Yao, T, Huang, J.
登録日2019-01-22
公開日2019-02-27
最終更新日2019-04-10
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of the crosstalk between histone H2B monoubiquitination and H3 lysine 79 methylation on nucleosome.
Cell Res., 29, 2019
2JZI
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BU of 2jzi by Molmil
Structure of Calmodulin complexed with the Calmodulin Binding Domain of Calcineurin
分子名称: CALCIUM ION, Calmodulin, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
著者Chyan, C, Huang, J, Irene, D, Lin, T.
登録日2008-01-09
公開日2009-01-13
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of Calmodulin complexed with the Calmodulin Binding Domain of Calcineurin
To be Published
7E3M
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BU of 7e3m by Molmil
RORgamma LBD complexed with Panaxatriol and SRC2.2
分子名称: (3R,5R,6S,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2R)-2,6,6-trimethyloxan-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6,12-triol, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, Nuclear receptor ROR-gamma
著者Liu, Z.H, Huang, J, Lu, W.Q, Tang, Y, Wu, Z.R.
登録日2021-02-09
公開日2022-03-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of human RORgammat LBD with SRC2.2 at 2.80 Angstroms resolution
To Be Published
7CWY
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BU of 7cwy by Molmil
Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP
分子名称: Decarboxylase
著者Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R.
登録日2020-09-01
公開日2021-09-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP
to be published
7CX0
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BU of 7cx0 by Molmil
Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor carbidopa
分子名称: CARBIDOPA, Decarboxylase, PYRIDOXAL-5'-PHOSPHATE
著者Yu, X, Gong, M, Huang, J, Liu, W, Chen, C, Guo, R.
登録日2020-09-01
公開日2021-09-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Crystal structure of a tyrosine decarboxylase from Enterococcus faecalis in complex with the cofactor PLP and inhibitor carbidopa
to be published

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