7JJO

Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound Beta1-Adrenergic Receptor

Summary for 7JJO

Entry DOI	10.2210/pdb7jjo/pdb
EMDB information	22357
Descriptor	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Nanobody 35, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... (6 entities in total)
Functional Keywords	gs protein, gpcr-gs complex, agonist, signaling protein
Biological source	Bos taurus (Bovine) More
Total number of polymer chains	5
Total formula weight	163136.03
Authors	Su, M.,Zhu, L.,Zhang, Y.,Paknejad, N.,Dey, R.,Huang, J.,Lee, M.Y.,Williams, D.,Jordan, K.D.,Eng, E.T.,Ernst, O.P.,Meyerson, J.R.,Hite, R.K.,Walz, T.,Liu, W.,Huang, X.Y. (deposition date: 2020-07-27, release date: 2020-09-02, Last modification date: 2020-10-14)
Primary citation	Su, M.,Zhu, L.,Zhang, Y.,Paknejad, N.,Dey, R.,Huang, J.,Lee, M.Y.,Williams, D.,Jordan, K.D.,Eng, E.T.,Ernst, O.P.,Meyerson, J.R.,Hite, R.K.,Walz, T.,Liu, W.,Huang, X.Y. Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound beta 1 -Adrenergic Receptor. Mol.Cell, 80:59-, 2020 Cited by PubMed: 32818430 DOI: 10.1016/j.molcel.2020.08.001 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.6 Å)

Structure validation