6MYV

Sialidase26 co-crystallized with DANA-Gc

Summary for 6MYV

Entry DOI	10.2210/pdb6myv/pdb
Descriptor	Sialidase26, 2,6-anhydro-3,5-dideoxy-5-[(hydroxyacetyl)amino]-D-glycero-L-altro-non-2-enonic acid (3 entities in total)
Functional Keywords	sialidase, microbiome, neu5gc, sialic acid, inflammation, neu5gc2en, dana, dana-gc, gc, hydrolase
Biological source	unidentified bacterium
Total number of polymer chains	4
Total formula weight	235073.81
Authors	Zaramela, L.S.,Martino, C.,Alisson-Silva, F.,Rees, S.D.,Diaz, S.L.,Chuzel, L.,Ganatra, M.B.,Taron, C.H.,Zuniga, C.,Huang, J.,Siegel, D.,Chang, G.,Varki, A.,Zengler, K. (deposition date: 2018-11-02, release date: 2019-10-02, Last modification date: 2023-10-11)
Primary citation	Zaramela, L.S.,Martino, C.,Alisson-Silva, F.,Rees, S.D.,Diaz, S.L.,Chuzel, L.,Ganatra, M.B.,Taron, C.H.,Secrest, P.,Zuniga, C.,Huang, J.,Siegel, D.,Chang, G.,Varki, A.,Zengler, K. Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates. Nat Microbiol, 4:2082-2089, 2019 Cited by PubMed: 31548686 DOI: 10.1038/s41564-019-0564-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation