8EVB
 
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8EV9
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8EVC
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5XMF
 | | Crystal structure of feline MHC class I for 2,1 angstrom | | 分子名称: | Beta-2-microglobulin, Gag polyprotein, MHC class I antigen alpha chain | | 著者 | Liang, R, Sun, Y, Wang, J, Wu, Y, Zhang, N, Xia, C. | | 登録日 | 2017-05-15 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Major Histocompatibility Complex Class I (FLA-E*01801) Molecular Structure in Domestic Cats Demonstrates Species-Specific Characteristics in Presenting Viral Antigen Peptides
J. Virol., 92, 2018
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8EV8
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4UIF
 | | Cryo-EM structure of Dengue virus serotype 2 in complex with antigen-binding fragments of human antibody 2D22 | | 分子名称: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 - LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN PVP94 07 - ENVELOPE PROTEIN, ... | | 著者 | Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.-N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe Junior, J.E, Lok, S.-M. | | 登録日 | 2015-03-30 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers.
Science, 349, 2015
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6IFU
 | | Cryo-EM structure of type III-A Csm-CTR2-dsDNA complex | | 分子名称: | CTR2, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | | 登録日 | 2018-09-21 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
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6LTU
 | | Crystal structure of Cas12i2 ternary complex with double Mg2+ bound in catalytic pocket | | 分子名称: | 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... | | 著者 | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | | 登録日 | 2020-01-23 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
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6IFR
 | | Type III-A Csm complex, Cryo-EM structure of Csm-NTR, ATP bound | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Type III-A CRISPR-associated RAMP protein Csm3, ... | | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | | 登録日 | 2018-09-21 | | 公開日 | 2018-12-12 | | 最終更新日 | 2019-01-23 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
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6IFK
 | | Cryo-EM structure of type III-A Csm-CTR1 complex, AMPPNP bound | | 分子名称: | CTR1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | | 登録日 | 2018-09-20 | | 公開日 | 2018-12-12 | | 最終更新日 | 2019-01-23 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
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3RGZ
 | | Structural insight into brassinosteroid perception by BRI1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Chai, J, Han, Z, She, J, Wang, J, Cheng, W. | | 登録日 | 2011-04-11 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.281 Å) | | 主引用文献 | Structural insight into brassinosteroid perception by BRI1.
Nature, 474, 2011
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6IG0
 | | Type III-A Csm complex, Cryo-EM structure of Csm-CTR1, ATP bound | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CTR1, MAGNESIUM ION, ... | | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | | 登録日 | 2018-09-21 | | 公開日 | 2018-12-12 | | 最終更新日 | 2019-01-23 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
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4UI9
 | | Atomic structure of the human Anaphase-Promoting Complex | | 分子名称: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | | 著者 | Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | | 登録日 | 2015-03-27 | | 公開日 | 2015-06-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
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4UIH
 | | Cryo-EM structure of Dengue virus serotype 2 strain New Guinea-C complexed with human antibody 2D22 Fab at 37 degree C. The Fab molecules were added to the virus before 37 degree C incubation. | | 分子名称: | ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -HEAVY CHAIN, ANTIGEN-BINDING FRAGMENT OF HUMAN ANTIBODY 2D22 -LIGHT CHAIN, DENGUE VIRUS SEROTYPE 2 STRAIN NEW GUINEA-C E PROTEIN ECTODOMAIN | | 著者 | Fibriansah, G, Ibarra, K.D, Ng, T.-S, Smith, S.A, Tan, J.L, Lim, X.N, Ooi, J.S.G, Kostyuchenko, V.A, Wang, J, de Silva, A.M, Harris, E, Crowe, J.E, Lok, S.-M. | | 登録日 | 2015-03-30 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (20 Å) | | 主引用文献 | Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers.
Science, 349, 2015
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7D72
 | | Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-Mannose | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, MAGNESIUM ION, Mannose-1-phosphate guanyltransferase alpha, ... | | 著者 | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, Cai, X, Mo, X, Gao, N, Jia, D. | | 登録日 | 2020-10-02 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis.
Nat.Struct.Mol.Biol., 28, 2021
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7D73
 | | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (State I) | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, GUANOSINE-5'-TRIPHOSPHATE, Mannose-1-phosphate guanyltransferase alpha, ... | | 著者 | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, Cai, X, Mo, X, Gao, N, Jia, D. | | 登録日 | 2020-10-02 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis.
Nat.Struct.Mol.Biol., 28, 2021
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7D74
 | | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state II) | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Mannose-1-phosphate guanyltransferase alpha, Mannose-1-phosphate guanyltransferase beta | | 著者 | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, cai, X, Mo, X, Gao, N, Jia, D. | | 登録日 | 2020-10-02 | | 公開日 | 2021-05-19 | | 最終更新日 | 2021-12-01 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis.
Nat.Struct.Mol.Biol., 28, 2021
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6IFY
 | | Type III-A Csm complex, Cryo-EM structure of Csm-CTR1 | | 分子名称: | CTR1, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | | 登録日 | 2018-09-21 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
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6IFL
 | | Cryo-EM structure of type III-A Csm-NTR complex | | 分子名称: | NTR, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | | 登録日 | 2018-09-20 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
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6LTR
 | | Crystal structure of Cas12i2 ternary complex with single Mg2+ bound in catalytic pocket | | 分子名称: | 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... | | 著者 | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | | 登録日 | 2020-01-23 | | 公開日 | 2020-10-28 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
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6LU0
 | | Crystal structure of Cas12i2 ternary complex with 12 nt spacer | | 分子名称: | Cas12i2, DNA (5'-D(*GP*CP*CP*GP*CP*TP*TP*TP*CP*TP*T)-3'), DNA (5'-D(*GP*CP*TP*TP*GP*CP*TP*CP*TP*GP*TP*TP*GP*AP*AP*AP*GP*CP*GP*GP*C)-3'), ... | | 著者 | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | | 登録日 | 2020-01-24 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
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8FHD
 | | Cryo-EM structure of human voltage-gated sodium channel Nav1.6 | | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, (5E,17R,20S)-23-amino-20-hydroxy-14,20-dioxo-15,19,21-trioxa-20lambda~5~-phosphatricos-5-en-17-yl hexadecanoate, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... | | 著者 | Fan, X, Huang, J, Yan, N. | | 登録日 | 2022-12-14 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structure of human voltage-gated sodium channel Na v 1.6.
Proc.Natl.Acad.Sci.USA, 120, 2023
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6AEI
 | | Cryo-EM structure of the receptor-activated TRPC5 ion channel | | 分子名称: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... | | 著者 | Duan, J, Li, Z, Li, J, Zhang, J. | | 登録日 | 2018-08-05 | | 公開日 | 2019-08-07 | | 最終更新日 | 2019-08-14 | | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | | 主引用文献 | Cryo-EM structure of TRPC5 at 2.8- angstrom resolution reveals unique and conserved structural elements essential for channel function.
Sci Adv, 5, 2019
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6LTP
 | | Crystal structure of Cas12i2 binary complex | | 分子名称: | Cas12i2, crRNA (56-mer RNA) | | 著者 | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | | 登録日 | 2020-01-23 | | 公開日 | 2020-10-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2.
Nat Commun, 11, 2020
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7YRZ
 | | Crystal structure of HCoV 229E main protease in complex with PF07321332 | | 分子名称: | (1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide, 3C-like proteinase | | 著者 | Zhou, Y.R, Zeng, P, Zhou, X.L, Lin, C, Zhang, J, Yin, X.S, Li, J. | | 登録日 | 2022-08-11 | | 公開日 | 2023-08-16 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Structural basis of main proteases of HCoV-229E bound to inhibitor PF-07304814 and PF-07321332.
Biochem.Biophys.Res.Commun., 657, 2023
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