8FHD

Cryo-EM structure of human voltage-gated sodium channel Nav1.6

Summary for 8FHD

• Entry DOI: 10.2210/pdb8fhd/pdb
• EMDB information: 29082
• Descriptor: Sodium channel protein type 8 subunit alpha, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, ... (12 entities in total)
• Functional Keywords: voltage-gated sodium channel, nav1.6, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 263824.27

Authors

Fan, X.,Huang, J.,Yan, N. (deposition date: 2022-12-14, release date: 2023-02-08)

• Primary citation: Fan, X.,Huang, J.,Jin, X.,Yan, N.; Cryo-EM structure of human voltage-gated sodium channel Na v 1.6.; Proc.Natl.Acad.Sci.USA, 120:e2220578120-e2220578120, 2023; PubMed: 36696443; DOI: 10.1073/pnas.2220578120

Experimental method

ELECTRON MICROSCOPY (3.1 Å)