8J6I
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![BU of 8j6i by Molmil](/molmil-images/mine/8j6i) | Cryo-EM structure of thehydroxycarboxylic acid receptor 2-Gi protein complex bound MK-6892 | 分子名称: | 2-[[2,2-dimethyl-3-[3-(5-oxidanylpyridin-2-yl)-1,2,4-oxadiazol-5-yl]propanoyl]amino]cyclohexene-1-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yuan, Q, Zhu, S, Duan, J, Xu, H.E, Duan, X. | 登録日 | 2023-04-26 | 公開日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2. Cell Rep, 42, 2023
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8J6L
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![BU of 8j6l by Molmil](/molmil-images/mine/8j6l) | Cryo-EM structure of thehydroxycarboxylic acid receptor 2-Gi protein complex bound niacin | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Yuan, Q, Zhu, S, Duan, J, Xu, H.E, Duan, X. | 登録日 | 2023-04-26 | 公開日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2. Cell Rep, 42, 2023
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8J6J
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![BU of 8j6j by Molmil](/molmil-images/mine/8j6j) | Cryo-EM structure of thehydroxycarboxylic acid receptor 2-Gi protein complex bound with GSK256073 | 分子名称: | 8-chloranyl-3-pentyl-7H-purine-2,6-dione, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yuan, Q, Zhu, S, Duan, J, Xu, H.E, Duan, X. | 登録日 | 2023-04-26 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Molecular recognition of niacin and lipid-lowering drugs by the human hydroxycarboxylic acid receptor 2. Cell Rep, 42, 2023
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7CJF
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![BU of 7cjf by Molmil](/molmil-images/mine/7cjf) | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ... | 著者 | Guo, Y, Li, X, Zhang, G, Fu, D, Schweizer, L, Zhang, H, Rao, Z. | 登録日 | 2020-07-10 | 公開日 | 2020-11-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.108 Å) | 主引用文献 | A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. Nat Commun, 12, 2021
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8GS5
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![BU of 8gs5 by Molmil](/molmil-images/mine/8gs5) | Crystal structure of a constitutively active mutant of human IDH3 holoenzyme in apo form | 分子名称: | Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ... | 著者 | Sun, P, Chen, X, Ding, J. | 登録日 | 2022-09-04 | 公開日 | 2022-11-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (4.486 Å) | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRD
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![BU of 8grd by Molmil](/molmil-images/mine/8grd) | Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ADP and Mg | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ... | 著者 | Chen, X, Sun, P, Ding, J. | 登録日 | 2022-09-01 | 公開日 | 2022-11-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.699 Å) | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRG
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8GRH
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![BU of 8grh by Molmil](/molmil-images/mine/8grh) | Crystal structure of a constitutively active mutant of the alpha gamma heterodimer of human IDH3 in complex with CIT | 分子名称: | CITRIC ACID, Human IDH3 alpha subunit, Isocitrate dehydrogenase [NAD] subunit gamma, ... | 著者 | Sun, P, Chen, X, Ding, J. | 登録日 | 2022-09-01 | 公開日 | 2022-11-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.506 Å) | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRU
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![BU of 8gru by Molmil](/molmil-images/mine/8gru) | Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca | 分子名称: | CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ... | 著者 | Sun, P, Chen, X, Ding, J. | 登録日 | 2022-09-02 | 公開日 | 2022-11-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.847 Å) | 主引用文献 | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRB
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6AAU
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![BU of 6aau by Molmil](/molmil-images/mine/6aau) | |
6AAS
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7WP1
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![BU of 7wp1 by Molmil](/molmil-images/mine/7wp1) | Cryo-EM structure of SARS-CoV-2 Mu S6P trimer in complex with neutralizing antibody VacW-209 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VacW-209 heavy chain, ... | 著者 | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | 登録日 | 2022-01-22 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.77 Å) | 主引用文献 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209. Cell Res., 32, 2022
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7WP5
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![BU of 7wp5 by Molmil](/molmil-images/mine/7wp5) | Cryo-EM structure of SARS-CoV-2 Omicron S6P trimer in complex with neutralizing antibody VacW-209 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spikeprotein S1, VacW-209 heavy chain, ... | 著者 | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | 登録日 | 2022-01-22 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209. Cell Res., 32, 2022
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7WON
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![BU of 7won by Molmil](/molmil-images/mine/7won) | Cryo-EM structure of SARS-CoV-2 S2P trimer in complex with neutralizing antibody VacW-209 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VacW-209 heavy chain, ... | 著者 | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | 登録日 | 2022-01-22 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209. Cell Res., 32, 2022
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7WP2
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![BU of 7wp2 by Molmil](/molmil-images/mine/7wp2) | Cryo-EM structure of SARS-CoV-2 C.1.2 S6P trimer in complex with neutralizing antibody VacW-209 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, VacW-209 heavy chain, ... | 著者 | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | 登録日 | 2022-01-22 | 公開日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209. Cell Res., 32, 2022
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7WP0
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![BU of 7wp0 by Molmil](/molmil-images/mine/7wp0) | Cryo-EM structure of SARS-CoV-2 Delta S6P trimer in complex with neutralizing antibody VacW-209 (local refinement) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IG c335_light_IGLV1-40_IGLJ3, Spike protein S1, ... | 著者 | Zheng, Q, Sun, H, Ju, B, Zhang, Z, Li, S, Xia, N. | 登録日 | 2022-01-22 | 公開日 | 2022-07-20 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209. Cell Res., 32, 2022
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8J5Z
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![BU of 8j5z by Molmil](/molmil-images/mine/8j5z) | The cryo-EM structure of the TwOSC1 tetramer | 分子名称: | Terpene cyclase/mutase family member, octyl beta-D-glucopyranoside | 著者 | Ma, X, Yuru, T, Yunfeng, L, Jiang, T. | 登録日 | 2023-04-24 | 公開日 | 2023-11-01 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (4.75 Å) | 主引用文献 | Structural and Catalytic Insight into the Unique Pentacyclic Triterpene Synthase TwOSC. Angew.Chem.Int.Ed.Engl., 62, 2023
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7CRF
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![BU of 7crf by Molmil](/molmil-images/mine/7crf) | Crystal structure of human TLR8 in complex with CU-CPD107 | 分子名称: | 1-[2-(ethoxymethyl)-4-iodanyl-5-phenyl-imidazol-1-yl]-2-methyl-propan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 8, ... | 著者 | Sakaniwa, K, Tanji, H, Ohto, U, Shimizu, T. | 登録日 | 2020-08-13 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists. Nat Commun, 12, 2021
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7EVR
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![BU of 7evr by Molmil](/molmil-images/mine/7evr) | Crystal structure of hnRNP L RRM2 in complex with SETD2 | 分子名称: | Heterogeneous nuclear ribonucleoprotein L, SHI domain from Histone-lysine N-methyltransferase SETD2 | 著者 | Li, F.D, Wang, S.M. | 登録日 | 2021-05-22 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing. Nat Commun, 12, 2021
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7EVS
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![BU of 7evs by Molmil](/molmil-images/mine/7evs) | Crystal structure of hnRNP LL RRM2 in complex with SETD2 | 分子名称: | Heterogeneous nuclear ribonucleoprotein L-like, SHI domain from Histone-lysine N-methyltransferase SETD2, SULFATE ION | 著者 | Li, F.D, Wang, S.M. | 登録日 | 2021-05-22 | 公開日 | 2021-10-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing. Nat Commun, 12, 2021
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6L42
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![BU of 6l42 by Molmil](/molmil-images/mine/6l42) | |
6MR5
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![BU of 6mr5 by Molmil](/molmil-images/mine/6mr5) | |
7DEO
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![BU of 7deo by Molmil](/molmil-images/mine/7deo) | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Spike protein S1, ... | 著者 | Fu, D, Zhang, G, Li, X, Rao, Z, Guo, Y. | 登録日 | 2020-11-04 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
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7DET
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![BU of 7det by Molmil](/molmil-images/mine/7det) | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | 著者 | Wang, Y, Zhang, G, Li, X, Rao, Z, Guo, Y. | 登録日 | 2020-11-05 | 公開日 | 2021-03-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes. Plos Biol., 19, 2021
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