8J5Z

The cryo-EM structure of the TwOSC1 tetramer

Summary for 8J5Z

Entry DOI	10.2210/pdb8j5z/pdb
EMDB information	35996
Descriptor	Terpene cyclase/mutase family member, octyl beta-D-glucopyranoside (2 entities in total)
Functional Keywords	oxidosqualene cyclase, tripterygium wilfordii hook. f., twosc1, friedelin, cryo-em structure, plant protein
Biological source	Tripterygium wilfordii
Total number of polymer chains	4
Total formula weight	354019.48
Authors	Ma, X.,Yuru, T.,Yunfeng, L.,Jiang, T. (deposition date: 2023-04-24, release date: 2023-11-01, Last modification date: 2024-01-03)
Primary citation	Luo, Y.,Ma, X.,Qiu, Y.,Lu, Y.,Shen, S.,Li, Y.,Gao, H.,Chen, K.,Zhou, J.,Hu, T.,Tu, L.,Zhao, H.,Li, D.,Leng, F.,Gao, W.,Jiang, T.,Liu, C.,Huang, L.,Wu, R.,Tong, Y. Structural and Catalytic Insight into the Unique Pentacyclic Triterpene Synthase TwOSC. Angew.Chem.Int.Ed.Engl., 62:e202313429-e202313429, 2023 Cited by PubMed: 37840440 DOI: 10.1002/anie.202313429 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.75 Å)

Structure validation