7EVR

Crystal structure of hnRNP L RRM2 in complex with SETD2

Summary for 7EVR

Entry DOI	10.2210/pdb7evr/pdb
Descriptor	Heterogeneous nuclear ribonucleoprotein L, SHI domain from Histone-lysine N-methyltransferase SETD2 (3 entities in total)
Functional Keywords	complex, rna binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	30828.80
Authors	Li, F.D.,Wang, S.M. (deposition date: 2021-05-22, release date: 2021-10-20, Last modification date: 2023-11-29)
Primary citation	Bhattacharya, S.,Wang, S.,Reddy, D.,Shen, S.,Zhang, Y.,Zhang, N.,Li, H.,Washburn, M.P.,Florens, L.,Shi, Y.,Workman, J.L.,Li, F. Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing. Nat Commun, 12:6452-6452, 2021 Cited by PubMed: 34750379 DOI: 10.1038/s41467-021-26799-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation