7EVS

Crystal structure of hnRNP LL RRM2 in complex with SETD2

Summary for 7EVS

• Entry DOI: 10.2210/pdb7evs/pdb
• Descriptor: Heterogeneous nuclear ribonucleoprotein L-like, SHI domain from Histone-lysine N-methyltransferase SETD2, SULFATE ION, ... (4 entities in total)
• Functional Keywords: complex, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 28056.40

Authors

Li, F.D.,Wang, S.M. (deposition date: 2021-05-22, release date: 2021-10-20, Last modification date: 2023-11-29)

• Primary citation: Bhattacharya, S.,Wang, S.,Reddy, D.,Shen, S.,Zhang, Y.,Zhang, N.,Li, H.,Washburn, M.P.,Florens, L.,Shi, Y.,Workman, J.L.,Li, F.; Structural basis of the interaction between SETD2 methyltransferase and hnRNP L paralogs for governing co-transcriptional splicing.; Nat Commun, 12:6452-6452, 2021; PubMed: 34750379; DOI: 10.1038/s41467-021-26799-3

Experimental method

X-RAY DIFFRACTION (1.6 Å)