7EVS

Crystal structure of hnRNP LL RRM2 in complex with SETD2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Heterogeneous nuclear ribonucleoprotein L-like	polymer	110	12623.6	2	UniProt (Q8WVV9) Pfam (PF11835)	Homo sapiens (Human)	hnRNPLL,Stromal RNA-regulating factor
2	C, D (C, D)	SHI domain from Histone-lysine N-methyltransferase SETD2	polymer	13	1308.5	2	UniProt (Q9BYW2)	Homo sapiens	HIF-1,Huntingtin yeast partner B,Huntingtin-interacting protein 1,HIP-1,Huntingtin-interacting protein B,Lysine N-methyltransferase 3A,Protein-lysine N-methyltransferase SETD2,SET domain-containing protein 2,hSET2,p231HBP
3	E, F (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	G, H, I, J (A, B, C, D)	water	water		18.0	352	Chemie (HOH)

Sequence modifications

A, B: 166 - 268 (UniProt: Q8WVV9)

PDB	External Database	Details
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
Met 165	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	27864.3
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	28056.4

*Water molecules are not included.