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3RPI
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BU of 3rpi by Molmil
Crystal Structure of Fab from 3BNC60, Highly Potent anti-HIV Antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain from highly potent anti-HIV neutralizing antibody, Light chain from highly potent anti-HIV neutralizing antibody
著者Diskin, R, Bjorkman, P.J.
登録日2011-04-26
公開日2011-07-20
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.648 Å)
主引用文献Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.
Science, 333, 2011
7RYU
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BU of 7ryu by Molmil
Anti-HIV neutralizing antibody Ab1303 Fab isolated from sequentially immunized mcaques
分子名称: Ab1303 Fab heavy chain, Ab1303 Fab light chain
著者Yang, Z, Bjorkman, P.J.
登録日2021-08-26
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7RYV
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BU of 7ryv by Molmil
Anti-HIV neutralizing antibody Ab1573 Fab isolated from sequentially immunized macaques
分子名称: Ab1573 Fab heavy chain, Ab1573 Fab light chain
著者Yang, Z, Bjorkman, P.J.
登録日2021-08-26
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
2GJ7
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BU of 2gj7 by Molmil
Crystal Structure of a gE-gI/Fc complex
分子名称: Glycoprotein E, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
著者Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J.
登録日2006-03-30
公開日2006-05-30
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (5 Å)
主引用文献Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging.
Plos Biol., 4, 2006
2GIY
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BU of 2giy by Molmil
Crystal Structure of the C-terminal domain of the HSV-1 gE ectodomain
分子名称: Glycoprotein E
著者Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J.
登録日2006-03-29
公開日2006-05-30
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging.
Plos Biol., 4, 2006
2GSG
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BU of 2gsg by Molmil
Crystal structure of the Fv fragment of a monoclonal antibody specific for poly-glutamine
分子名称: SULFATE ION, monoclonal antibody heavy chain, monoclonal antibody light chain
著者Li, P, Huey-Tubman, K.E, West Jr, A.P, Bennett, M.J, Bjorkman, P.J.
登録日2006-04-26
公開日2007-04-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of a polyQ-anti-polyQ complex reveals binding according to a linear lattice model.
Nat.Struct.Mol.Biol., 14, 2007
2GW5
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BU of 2gw5 by Molmil
Crystal Structure of LIR-2 (ILT4) at 1.8 : differences from LIR-1 (ILT2) in regions implicated in the binding of the Cytomegalovirus class I MHC homolog UL18
分子名称: ISOPROPYL ALCOHOL, Leukocyte immunoglobulin-like receptor subfamily B member 2 precursor
著者Willcox, B.E, Thomas, L.M, Chapman, T.L, Heikema, A.P, West, A.P, Bjorkman, P.J.
登録日2006-05-03
公開日2006-06-20
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of LIR-2 (ILT4) at 1.8 A: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18.
Bmc Struct.Biol., 2, 2002
4JDT
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BU of 4jdt by Molmil
Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
著者Scharf, L, Diskin, R, Bjorkman, P.J.
登録日2013-02-25
公開日2013-03-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JKP
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BU of 4jkp by Molmil
Restricting HIV-1 Pathways for Escape using Rationally-Designed Anti-HIV-1 Antibodies
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody 45-46M2, Light chain of antibody 45-46M2, ...
著者Diskin, R, Bjorkman, P.J.
登録日2013-03-11
公開日2013-05-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies.
J.Exp.Med., 210, 2013
4JDV
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BU of 4jdv by Molmil
Crystal structure of germ-line precursor of NIH45-46 Fab
分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ...
著者Diskin, R, Scharf, L, Bjorkman, P.J.
登録日2013-02-25
公開日2013-03-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.
Proc.Natl.Acad.Sci.USA, 110, 2013
7U0C
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BU of 7u0c by Molmil
Crystal structure of broadly neutralizing antibody HEPC3.4
分子名称: HEPC3.4 Fab Heavy Chain, HEPC3.4 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J.
登録日2022-02-17
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Nat Commun, 13, 2022
7U0B
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BU of 7u0b by Molmil
Crystal structure of broadly neutralizing antibody HEPC3.1
分子名称: HEPC3.1 Fab Heavy Chain, HEPC3.1 Fab Light Chain
著者Flyak, A.I, Bjorkman, P.J.
登録日2022-02-17
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Computational identification of HCV neutralizing antibodies with a common HCDR3 disulfide bond motif in the antibody repertoires of infected individuals.
Nat Commun, 13, 2022
7TQG
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BU of 7tqg by Molmil
Crystal Structure of IOMA Fab inferred germline
分子名称: IOMA iGL Fab Heavy Chain, IOMA iGL Fab Light Chain
著者Gristick, H.B, Bjorkman, P.J.
登録日2022-01-26
公開日2023-03-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献CD4 binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wild-type animals.
Sci Immunol, 8, 2023
7UCE
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BU of 7uce by Molmil
Structure of the anti-HIV-1 neutralizing antibody BG24 Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG24 Fab heavy chain, BG24 Fab light chain
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UCG
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Structure of the DU422 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24
分子名称: 10-1074 Fab heavy chain, 10-1074 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2022-09-07
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UCF
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Structure of the BG505 SOSIP.664 trimer in complex with neutralizing antibody Fab fragments 10-1074 and BG24
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Barnes, C.O, Bjorkman, P.J.
登録日2022-03-16
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献A naturally arising broad and potent CD4-binding site antibody with low somatic mutation.
Sci Adv, 8, 2022
7UGP
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BU of 7ugp by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 containing the N276 gp120 glycan- Class 1
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dam, K.A, Bjorkman, P.J.
登録日2022-03-25
公開日2022-11-09
最終更新日2022-11-16
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGO
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BU of 7ugo by Molmil
Cryo-EM structure of BG24 inferred germline Fabs with mature CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dam, K.A, Bjorkman, P.J.
登録日2022-03-25
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGQ
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BU of 7ugq by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline CDRL1 and 10-1074 Fabs in complex with HIV-1 Env 6405-SOSIP.664
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dam, K.A, Bjorkman, P.J.
登録日2022-03-25
公開日2022-11-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGN
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BU of 7ugn by Molmil
Cryo-EM structure of BG24 inferred germline Fabs with germline CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 - Class 1
分子名称: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Dam, K.A, Bjorkman, P.J.
登録日2022-03-25
公開日2022-10-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGM
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BU of 7ugm by Molmil
Crystal Structure of BG24-iGL CDR3mat Fab
分子名称: BG24-iGL CDR3mat Fab heavy chain, BG24-iGL CDR3mat Fab light chain
著者Dam, K.A, Barnes, C.O, Bjorkman, P.J.
登録日2022-03-25
公開日2022-11-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UZA
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BU of 7uza by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, HSW-1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HSW-1 Fab heavy chain, ...
著者Fan, C, Bjorkman, P.J.
登録日2022-05-08
公開日2022-12-07
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ7
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BU of 7uz7 by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-31
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-31 Fab heavy chain, ...
著者Fan, C, Bjorkman, P.J.
登録日2022-05-08
公開日2022-12-07
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ5
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Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-6 Fab heavy chain, M8a-6 Fab light chain, ...
著者Fan, C, Bjorkman, P.J.
登録日2022-05-08
公開日2022-12-07
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022
7UZ4
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Structure of the SARS-CoV-2 S 6P trimer in complex with the mouse antibody Fab fragment, M8a-3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, M8a-3 Fab heavy chain, ...
著者Fan, C, Bjorkman, P.J.
登録日2022-05-08
公開日2022-12-07
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Immunity, 55, 2022

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