6V99
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![BU of 6v99 by Molmil](/molmil-images/mine/6v99) | Agrobacterium tumefaciens ADP-Glucose pyrophosphorylase- S72D in the presence of sulfate | 分子名称: | Glucose-1-phosphate adenylyltransferase, SULFATE ION | 著者 | Zheng, Y, Alghamdi, M.A, Ballicora, M.A, Liu, D. | 登録日 | 2019-12-13 | 公開日 | 2020-12-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.287 Å) | 主引用文献 | Site-directed mutagenesis of Serine-72 reveals the location of the fructose 6-phosphate regulatory site of the Agrobacterium tumefaciens ADP-glucose pyrophosphorylase. Protein Sci., 31, 2022
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5CRL
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6YQ1
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![BU of 6yq1 by Molmil](/molmil-images/mine/6yq1) | FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH N-Methyl-N-(3-{[2-(2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylamino)-5-trifluoromethyl-pyrimidin-4-ylamino]-methyl}-pyridin-2-yl)-methanesulfonamide | 分子名称: | Focal adhesion kinase 1, SODIUM ION, SULFATE ION, ... | 著者 | Musil, D, Heinrich, T, Amaral, M. | 登録日 | 2020-04-16 | 公開日 | 2021-02-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.784 Å) | 主引用文献 | Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2. Cell Chem Biol, 28, 2021
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5CSY
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![BU of 5csy by Molmil](/molmil-images/mine/5csy) | Disproportionating enzyme 1 from Arabidopsis - acarbose soak | 分子名称: | 1,2-ETHANEDIOL, 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic, ... | 著者 | O'Neill, E.C, Stevenson, C.E.M, Tantanarat, K, Latousakis, D, Donaldson, M.I, Rejzek, M, Limpaseni, T, Smith, A.M, Field, R.A, Lawson, D.M. | 登録日 | 2015-07-23 | 公開日 | 2015-11-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1). J.Biol.Chem., 290, 2015
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6YR9
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5DB5
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![BU of 5db5 by Molmil](/molmil-images/mine/5db5) | Crystal structure of PLP-bound E. coli SufS (cysteine persulfide intermediate) in space group P21 | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, CYSTEINE, ... | 著者 | Arbing, M.A, Shin, A, Koo, C.W, Medrano-Soto, A, Eisenberg, D. | 登録日 | 2015-08-20 | 公開日 | 2016-08-24 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal structure of PLP-bound E. coli SufS (cysteine persulfide intermediate) in space group P21 To Be Published
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6YLA
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![BU of 6yla by Molmil](/molmil-images/mine/6yla) | Crystal structure of the SARS-CoV-2 receptor binding domain in complex with CR3022 Fab | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | 著者 | Huo, J, Zhao, Y, Ren, J, Zhou, D, Ginn, H.M, Fry, E.E, Owens, R, Stuart, D.I. | 登録日 | 2020-04-06 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike. Cell Host Microbe, 28, 2020
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5CUW
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6YK8
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6MGA
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6YOJ
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5CXV
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![BU of 5cxv by Molmil](/molmil-images/mine/5cxv) | Structure of the human M1 muscarinic acetylcholine receptor bound to antagonist Tiotropium | 分子名称: | (1R,2R,4S,5S,7S)-7-{[hydroxy(dithiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane, 1,2-ETHANEDIOL, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Sun, B, Feng, D, Li, X, Kobilka, T.S, Kobilka, B.K. | 登録日 | 2015-07-29 | 公開日 | 2016-03-09 | 最終更新日 | 2016-03-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of the M1 and M4 muscarinic acetylcholine receptors. Nature, 531, 2016
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1NMQ
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![BU of 1nmq by Molmil](/molmil-images/mine/1nmq) | Extendend Tethering: In Situ Assembly of Inhibitors | 分子名称: | 3-(3-{2-[(5-METHANESULFONYL-THIOPHENE-2-CARBONYL)-AMINO]-ETHYLDISULFANYLMETHYL}- BENZENESULFONYLAMINO)-4-OXO-PENTANOIC ACID, Caspase-3 | 著者 | Erlanson, D.A, Lam, J, Wiesmann, C, Luong, T.N, Simmons, R.L, DeLano, W, Choong, I.C, Flanagan, M, Lee, D, O'Brian, T. | 登録日 | 2003-01-10 | 公開日 | 2003-03-11 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | In situ assembly of enzyme inhibitors using extended tethering. Nat.Biotechnol., 21, 2003
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5CYI
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![BU of 5cyi by Molmil](/molmil-images/mine/5cyi) | CDK2/Cyclin A covalent complex with 6-(cyclohexylmethoxy)-N-(4-(vinylsulfonyl)phenyl)-9H-purin-2-amine (NU6300) | 分子名称: | 6-(cyclohexylmethoxy)-N-[4-(ethylsulfonyl)phenyl]-9H-purin-2-amine, Cyclin-A2, Cyclin-dependent kinase 2 | 著者 | Anscombe, E, Meschini, E, Vidal, R.M, Martin, M.P, Staunton, D, Geitmann, M, Danielson, U.H, Stanley, W.A, Wang, L.Z, Reuillon, T, Golding, B.T, Cano, C, Newell, D.R, Noble, M.E.M, Wedge, S.R, Endicott, J.A, Griffin, R.J. | 登録日 | 2015-07-30 | 公開日 | 2015-09-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification and Characterization of an Irreversible Inhibitor of CDK2. Chem.Biol., 22, 2015
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5D11
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![BU of 5d11 by Molmil](/molmil-images/mine/5d11) | Kinase domain of cSrc in complex with RL235 | 分子名称: | GLYCEROL, N-[3-({4-(4-methylpiperazin-1-yl)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl}oxy)phenyl]prop-2-enamide, Proto-oncogene tyrosine-protein kinase Src | 著者 | Becker, C, Gruetter, C, Engel, J, Rauh, D. | 登録日 | 2015-08-03 | 公開日 | 2015-09-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach. J.Med.Chem., 58, 2015
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6MCK
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![BU of 6mck by Molmil](/molmil-images/mine/6mck) | p97 D1D2 with CB5083 bound | 分子名称: | 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, Transitional endoplasmic reticulum ATPase | 著者 | Xia, D, Tang, W.K. | 登録日 | 2018-08-31 | 公開日 | 2019-01-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.77 Å) | 主引用文献 | Structural Basis of p97 Inhibition by the Site-Selective Anticancer Compound CB-5083. Mol. Pharmacol., 95, 2019
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5DH7
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![BU of 5dh7 by Molmil](/molmil-images/mine/5dh7) | Two divalent metal ions and conformational changes play roles in the hammerhead ribozyme cleavage reaction-G12A mutant in Mn2+ | 分子名称: | 5'-R(*GP*GP*GP*CP*GP*UP*DC*UP*GP*GP*GP*CP*AP*GP*UP*AP*CP*CP*CP*A)-3', MANGANESE (II) ION, RNA (48-MER) | 著者 | Mir, A, Chen, J, Neau, D, Golden, B.L. | 登録日 | 2015-08-29 | 公開日 | 2015-10-07 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.064 Å) | 主引用文献 | Two Divalent Metal Ions and Conformational Changes Play Roles in the Hammerhead Ribozyme Cleavage Reaction. Biochemistry, 54, 2015
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5CPT
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![BU of 5cpt by Molmil](/molmil-images/mine/5cpt) | Disproportionating enzyme 1 from Arabidopsis - beta cyclodextrin soak | 分子名称: | 1,2-ETHANEDIOL, 4-alpha-glucanotransferase DPE1, chloroplastic/amyloplastic, ... | 著者 | O'Neill, E.C, Stevenson, C.E.M, Tantanarat, K, Latousakis, D, Donaldson, M.I, Rejzek, M, Limpaseni, T, Smith, A.M, Field, R.A, Lawson, D.M. | 登録日 | 2015-07-21 | 公開日 | 2015-11-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Dissection of the Maltodextrin Disproportionation Cycle of the Arabidopsis Plastidial Disproportionating Enzyme 1 (DPE1). J.Biol.Chem., 290, 2015
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6UZN
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6UZS
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6VA9
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1OEO
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![BU of 1oeo by Molmil](/molmil-images/mine/1oeo) | PTP1B with the catalytic cysteine oxidized to sulfonic acid | 分子名称: | PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1 | 著者 | Salmeen, A, Andersen, J.N, Myers, M.P, Meng, T.C, Hinks, J.A, Tonks, N.K, Barford, D. | 登録日 | 2003-03-28 | 公開日 | 2003-06-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Redox Regulation of Protein Tyrosine Phosphatase Involves a Sulfenyl-Amide Intermediate Nature, 423, 2003
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5DFN
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![BU of 5dfn by Molmil](/molmil-images/mine/5dfn) | Structure of Tetrahymena Telomerase P45 C-terminal domain | 分子名称: | Telomerase associated protein p45 | 著者 | Chan, H, Cascio, D, Sawaya, M.R, Feigon, J. | 登録日 | 2015-08-27 | 公開日 | 2015-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions. Science, 350, 2015
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6M0F
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![BU of 6m0f by Molmil](/molmil-images/mine/6m0f) | X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) in substrate-free form | 分子名称: | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, Antibody fragment (9D5) Light chain, Antibody fragment (9D5) heavy chain, ... | 著者 | Shabareesh, P, Mallela, A.K, Joseph, D, Penmatsa, A. | 登録日 | 2020-02-21 | 公開日 | 2021-02-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12, 2021
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6LSV
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![BU of 6lsv by Molmil](/molmil-images/mine/6lsv) | Crystal structure of JOX2 in complex with 2OG, Fe, and JA | 分子名称: | 2-OXOGLUTARIC ACID, FE (III) ION, Probable 2-oxoglutarate-dependent dioxygenase At5g05600, ... | 著者 | Zhang, X, Wang, D, Liu, J. | 登録日 | 2020-01-20 | 公開日 | 2021-02-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.651 Å) | 主引用文献 | Structure-guided analysis of Arabidopsis JASMONATE-INDUCED OXYGENASE (JOX) 2 reveals key residues for recognition of jasmonic acid substrate by plant JOXs. Mol Plant, 14, 2021
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