6M0F

X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) in substrate-free form

Summary for 6M0F

Entry DOI	10.2210/pdb6m0f/pdb
Related	4M48 4XNX 4XP1 4XPH
Descriptor	Sodium-dependent dopamine transporter, Antibody fragment (9D5) Light chain, Antibody fragment (9D5) heavy chain, ... (8 entities in total)
Functional Keywords	neurotransmitter transporter, antibody fragment, membrane protein
Biological source	Drosophila melanogaster (Fruit fly) More
Total number of polymer chains	3
Total formula weight	107821.35
Authors	Shabareesh, P.,Mallela, A.K.,Joseph, D.,Penmatsa, A. (deposition date: 2020-02-21, release date: 2021-02-17, Last modification date: 2023-11-29)
Primary citation	Pidathala, S.,Mallela, A.K.,Joseph, D.,Penmatsa, A. Structural basis of norepinephrine recognition and transport inhibition in neurotransmitter transporters. Nat Commun, 12:2199-2199, 2021 Cited by PubMed: 33850134 DOI: 10.1038/s41467-021-22385-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation