4XNX
X-ray structure of Drosophila dopamine transporter in complex with reboxetine
Summary for 4XNX
Entry DOI | 10.2210/pdb4xnx/pdb |
Related | 4M48 4XP1 4XP4 4XP5 4XP6 4XP9 4XPA 4XPB 4XPF 4XPG 4XPH 4XPT |
Related PRD ID | PRD_900018 |
Descriptor | Transporter, antibody fragment light chain, Antibody fragment heavy chain, ... (9 entities in total) |
Functional Keywords | integral membrane protein, all-alpha helical antidepressant complex, transport protein-inhibitor complex, transport protein/inhibitor |
Biological source | Drosophila melanogaster (Fruit fly) More |
Total number of polymer chains | 3 |
Total formula weight | 110886.89 |
Authors | Aravind, P.,Wang, K.,Gouaux, E. (deposition date: 2015-01-16, release date: 2015-05-13, Last modification date: 2023-09-27) |
Primary citation | Penmatsa, A.,Wang, K.H.,Gouaux, E. X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine. Nat.Struct.Mol.Biol., 22:506-508, 2015 Cited by PubMed: 25961798DOI: 10.1038/nsmb.3029 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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