4XP5
X-ray structure of Drosophila dopamine transporter bound to cocaine analogue-RTI55
Summary for 4XP5
| Entry DOI | 10.2210/pdb4xp5/pdb |
| Related PRD ID | PRD_900001 |
| Descriptor | Dopamine transporter, isoform B, Antibody fragment heavy chain-protein, 9D5-heavy chain, Ighg protein, ... (9 entities in total) |
| Functional Keywords | integral membrane protein, membrane protein-transport protein complex, transport protein-inhibitor complex, transport protein/inhibitor |
| Biological source | Drosophila melanogaster (Fruit fly) More |
| Total number of polymer chains | 3 |
| Total formula weight | 108433.70 |
| Authors | Gouaux, E.,Penmatsa, A.,Wang, K. (deposition date: 2015-01-16, release date: 2015-05-06, Last modification date: 2020-07-29) |
| Primary citation | Wang, K.H.,Penmatsa, A.,Gouaux, E. Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521:322-327, 2015 Cited by PubMed: 25970245DOI: 10.1038/nature14431 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.3 Å) |
Structure validation
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