4XP9
X-ray structure of Drosophila dopamine transporter bound to psychostimulant D-amphetamine
Summary for 4XP9
| Entry DOI | 10.2210/pdb4xp9/pdb |
| Related | 4XNX 4XP1 4XP4 4XP5 4XP6 4XPA 4XPB 4XPF 4XPG 4XPH 4XPT |
| Related PRD ID | PRD_900001 |
| Descriptor | Transporter, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, SODIUM ION, ... (13 entities in total) |
| Functional Keywords | integral membrane protein, all-alpha helical antidepressant complex, membrane protein, protein transport, transport protein-inhibitor complex, transport protein/inhibitor |
| Biological source | Drosophila melanogaster (Fruit fly) More |
| Total number of polymer chains | 3 |
| Total formula weight | 109726.47 |
| Authors | Aravind, P.,Wang, K.,Gouaux, E. (deposition date: 2015-01-16, release date: 2015-05-06, Last modification date: 2023-09-27) |
| Primary citation | Wang, K.H.,Penmatsa, A.,Gouaux, E. Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521:322-327, 2015 Cited by PubMed: 25970245DOI: 10.1038/nature14431 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
Download full validation report
