4XPG
X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to beta-CFT or Win35428
Summary for 4XPG
Entry DOI | 10.2210/pdb4xpg/pdb |
Descriptor | Dopamine transporter, antibody fragment light chain, antibody fragment heavy chain, ... (7 entities in total) |
Functional Keywords | all alpha-helical integral membrane protein, transport protein-inhibitor complex, transport protein/inhibitor |
Biological source | Drosophila melanogaster More |
Total number of polymer chains | 3 |
Total formula weight | 113904.73 |
Authors | Penmatsa, A.,Wang, K.H.,Gouaux, E. (deposition date: 2015-01-16, release date: 2015-05-06, Last modification date: 2023-09-27) |
Primary citation | Wang, K.H.,Penmatsa, A.,Gouaux, E. Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521:322-327, 2015 Cited by PubMed: 25970245DOI: 10.1038/nature14431 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.21 Å) |
Structure validation
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