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4XPG

X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to beta-CFT or Win35428

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dopamine transporterpolymer54360925.61Pfam (PF00209)
UniProt (by SIFTS) (Q7K4Y6)
Drosophila melanogaster
2B
(L)
antibody fragment light chainpolymer23725840.61Mus musculus
3C
(H)
antibody fragment heavy chainpolymer24126006.41Mus musculus
4D
(A)
methyl (1R,2S,3S,5S)-3-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylatenon-polymer277.31Chemie (42L)
5E, F
(A)
CHOLESTEROLnon-polymer386.72Chemie (CLR)
6G
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
7H, I
(A)
SODIUM IONnon-polymer23.02Chemie (NA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight112772.7
Non-Polymers*Number of molecules6
Total formula weight1132.1
All*Total formula weight113904.7
*Water molecules are not included.

242500

PDB entries from 2025-10-01

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