4XPG

X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to beta-CFT or Win35428

Summary for 4XPG

Entry DOI	10.2210/pdb4xpg/pdb
Descriptor	Dopamine transporter, antibody fragment light chain, antibody fragment heavy chain, ... (7 entities in total)
Functional Keywords	all alpha-helical integral membrane protein, transport protein-inhibitor complex, transport protein/inhibitor
Biological source	Drosophila melanogaster More
Total number of polymer chains	3
Total formula weight	113904.73
Authors	Penmatsa, A.,Wang, K.H.,Gouaux, E. (deposition date: 2015-01-16, release date: 2015-05-06, Last modification date: 2023-09-27)
Primary citation	Wang, K.H.,Penmatsa, A.,Gouaux, E. Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521:322-327, 2015 Cited by PubMed: 25970245 DOI: 10.1038/nature14431 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.21 Å)

Structure validation