4XPF
X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to RTI-55
Summary for 4XPF
Entry DOI | 10.2210/pdb4xpf/pdb |
Related | 4XNU 4XNX 4XP1 4XP4 4XP5 4XP6 4XP9 4XPA 4XPB 4XPG 4XPH 4XPT |
Descriptor | Dopamine transporter-protein, ANTIBODY FRAGMENT HEAVY CHAIN-PROTEIN, 9D5-HEAVY CHAIN, ANTIBODY FRAGMENT LIGHT CHAIN-PROTEIN, 9D5-LIGHT CHAIN, ... (10 entities in total) |
Functional Keywords | all alpha-helical integral membrane protein, transport protein-inhibitor complex, transport protein/inhibitor |
Biological source | Drosophila melanogaster More |
Total number of polymer chains | 3 |
Total formula weight | 114572.32 |
Authors | Penmatsa, A.,Wang, K.H.,Gouaux, E. (deposition date: 2015-01-16, release date: 2015-05-06, Last modification date: 2023-09-27) |
Primary citation | Wang, K.H.,Penmatsa, A.,Gouaux, E. Neurotransmitter and psychostimulant recognition by the dopamine transporter. Nature, 521:322-327, 2015 Cited by PubMed: 25970245DOI: 10.1038/nature14431 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.273 Å) |
Structure validation
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