4M48
X-ray structure of dopamine transporter elucidates antidepressant mechanism
Summary for 4M48
Entry DOI | 10.2210/pdb4m48/pdb |
Descriptor | Transporter, 9D5 antibody, light chain, 9D5 antibody, heavy chain, ... (8 entities in total) |
Functional Keywords | slc6, neurotransmitter transporter, transport protein |
Biological source | Drosophila melanogaster (Fruit fly) More |
Total number of polymer chains | 3 |
Total formula weight | 113432.93 |
Authors | Gouaux, E.,Penmatsa, A.,Wang, K. (deposition date: 2013-08-06, release date: 2013-09-18, Last modification date: 2023-09-20) |
Primary citation | Penmatsa, A.,Wang, K.H.,Gouaux, E. X-ray structure of dopamine transporter elucidates antidepressant mechanism. Nature, 503:85-90, 2013 Cited by PubMed: 24037379DOI: 10.1038/nature12533 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.955 Å) |
Structure validation
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