4XNX

X-ray structure of Drosophila dopamine transporter in complex with reboxetine

Summary for 4XNX

Entry DOI	10.2210/pdb4xnx/pdb
Related	4M48 4XP1 4XP4 4XP5 4XP6 4XP9 4XPA 4XPB 4XPF 4XPG 4XPH 4XPT
Related PRD ID	PRD_900018
Descriptor	Transporter, antibody fragment light chain, Antibody fragment heavy chain, ... (9 entities in total)
Functional Keywords	integral membrane protein, all-alpha helical antidepressant complex, transport protein-inhibitor complex, transport protein/inhibitor
Biological source	Drosophila melanogaster (Fruit fly) More
Total number of polymer chains	3
Total formula weight	110886.89
Authors	Aravind, P.,Wang, K.,Gouaux, E. (deposition date: 2015-01-16, release date: 2015-05-13, Last modification date: 2023-09-27)
Primary citation	Penmatsa, A.,Wang, K.H.,Gouaux, E. X-ray structures of Drosophila dopamine transporter in complex with nisoxetine and reboxetine. Nat.Struct.Mol.Biol., 22:506-508, 2015 Cited by PubMed: 25961798 DOI: 10.1038/nsmb.3029 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation