8HUP
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![BU of 8hup by Molmil](/molmil-images/mine/8hup) | X-ray structure of human PPAR gamma ligand binding domain-seladelpar-SRC1 coactivator peptide co-crystals obtained by co-crystallization | 分子名称: | 15-meric peptide from Nuclear receptor coactivator 1, Isoform 1 of Peroxisome proliferator-activated receptor gamma, Seladelpar | 著者 | Kamata, S, Honda, A, Machida, Y, Uchii, K, Shiiyama, Y, Masuda, R, Oyama, T, Ishii, I. | 登録日 | 2022-12-24 | 公開日 | 2023-08-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Functional and Structural Insights into the Human PPAR alpha / delta / gamma Targeting Preferences of Anti-NASH Investigational Drugs, Lanifibranor, Seladelpar, and Elafibranor. Antioxidants, 12, 2023
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8HUM
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![BU of 8hum by Molmil](/molmil-images/mine/8hum) | X-ray structure of human PPAR gamma ligand binding domain-lanifibranor-SRC1 coactivator peptide co-crystals obtained by co-crystallization | 分子名称: | 15-meric peptide from Nuclear receptor coactivator 1, 4-[1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl]butanoic acid, Isoform 1 of Peroxisome proliferator-activated receptor gamma | 著者 | Kamata, S, Honda, A, Machida, Y, Uchii, K, Shiiyama, Y, Masuda, R, Oyama, T, Ishii, I. | 登録日 | 2022-12-24 | 公開日 | 2023-08-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Functional and Structural Insights into the Human PPAR alpha / delta / gamma Targeting Preferences of Anti-NASH Investigational Drugs, Lanifibranor, Seladelpar, and Elafibranor. Antioxidants, 12, 2023
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8HUO
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![BU of 8huo by Molmil](/molmil-images/mine/8huo) | X-ray structure of human PPAR delta ligand binding domain-seladelpar co-crystals obtained by co-crystallization | 分子名称: | Peroxisome proliferator-activated receptor delta, Seladelpar | 著者 | Kamata, S, Honda, A, Machida, Y, Uchii, K, Shiiyama, Y, Masuda, R, Oyama, T, Ishii, I. | 登録日 | 2022-12-24 | 公開日 | 2023-08-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.671 Å) | 主引用文献 | Functional and Structural Insights into the Human PPAR alpha / delta / gamma Targeting Preferences of Anti-NASH Investigational Drugs, Lanifibranor, Seladelpar, and Elafibranor. Antioxidants, 12, 2023
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4XMO
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![BU of 4xmo by Molmil](/molmil-images/mine/4xmo) | Crystal structure of c-Met in complex with (R)-5-(8-fluoro-3-(1-fluoro-1-(3-methoxyquinolin-6-yl)ethyl)-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-3-methylisoxazole | 分子名称: | 6-{(1R)-1-fluoro-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-methoxyquinoline, Hepatocyte growth factor receptor | 著者 | Whittington, D.A, Long, A.M. | 登録日 | 2015-01-14 | 公開日 | 2015-03-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Discovery of Potent and Selective 8-Fluorotriazolopyridine c-Met Inhibitors. J.Med.Chem., 58, 2015
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6YPE
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![BU of 6ype by Molmil](/molmil-images/mine/6ype) | |
4XYF
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![BU of 4xyf by Molmil](/molmil-images/mine/4xyf) | Crystal structure of c-Met in complex with (S)-5-(8-fluoro-3-(1-(3-(2-methoxyethoxy)quinolin-6-yl)ethyl)-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-3-methylisoxazole | 分子名称: | 6-{(1S)-1-[8-fluoro-6-(3-methyl-1,2-oxazol-5-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)quinoline, Hepatocyte growth factor receptor | 著者 | Whittington, D.A, Long, A.M. | 登録日 | 2015-02-02 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Discovery of Potent and Selective 8-Fluorotriazolopyridine c-Met Inhibitors. J.Med.Chem., 58, 2015
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6X1J
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6KEP
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![BU of 6kep by Molmil](/molmil-images/mine/6kep) | Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in 17beta-estradiol- and glutathione-bound form | 分子名称: | ESTRADIOL, GLUTATHIONE, Glutathione S-transferase E14 | 著者 | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | 登録日 | 2019-07-04 | 公開日 | 2019-10-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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6KEO
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![BU of 6keo by Molmil](/molmil-images/mine/6keo) | Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in 17beta-estradiol-bound form | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ESTRADIOL, Glutathione S-transferase E14 | 著者 | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | 登録日 | 2019-07-04 | 公開日 | 2019-10-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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8EB2
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![BU of 8eb2 by Molmil](/molmil-images/mine/8eb2) | |
3H1V
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![BU of 3h1v by Molmil](/molmil-images/mine/3h1v) | Human glucokinase in complex with a synthetic activator | 分子名称: | 1-({5-[4-(methylsulfonyl)phenoxy]-2-pyridin-2-yl-1H-benzimidazol-6-yl}methyl)pyrrolidine-2,5-dione, Glucokinase, SODIUM ION, ... | 著者 | Kamata, K, Takahashi, K. | 登録日 | 2009-04-14 | 公開日 | 2009-10-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators. Bioorg.Med.Chem., 17, 2009
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6KEM
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![BU of 6kem by Molmil](/molmil-images/mine/6kem) | Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in apo-form 2 | 分子名称: | Glutathione S-transferase E14 | 著者 | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | 登録日 | 2019-07-04 | 公開日 | 2019-10-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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6KEL
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![BU of 6kel by Molmil](/molmil-images/mine/6kel) | Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in apo-form | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glutathione S-transferase E14 | 著者 | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Senda, T, Niwa, R. | 登録日 | 2019-07-04 | 公開日 | 2019-10-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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6KEQ
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![BU of 6keq by Molmil](/molmil-images/mine/6keq) | Crystal structure of D113A mutant of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in apo-form | 分子名称: | Glutathione S-transferase E14 | 著者 | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | 登録日 | 2019-07-04 | 公開日 | 2019-10-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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6KER
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![BU of 6ker by Molmil](/molmil-images/mine/6ker) | Crystal structure of D113A mutant of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in glutathione-bound form | 分子名称: | GLUTATHIONE, Glutathione S-transferase E14 | 著者 | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | 登録日 | 2019-07-04 | 公開日 | 2019-10-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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6KEN
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![BU of 6ken by Molmil](/molmil-images/mine/6ken) | Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in glutathione-bound form | 分子名称: | GLUTATHIONE, Glutathione S-transferase E14 | 著者 | Koiwai, K, Inaba, K, Morohashi, K, Yumoto, F, Niwa, R, Senda, T. | 登録日 | 2019-07-04 | 公開日 | 2019-10-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo. J.Biol.Chem., 295, 2020
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8HHV
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![BU of 8hhv by Molmil](/molmil-images/mine/8hhv) | endo-alpha-D-arabinanase EndoMA1 from Microbacterium arabinogalactanolyticum | 分子名称: | CALCIUM ION, GLYCEROL, SODIUM ION, ... | 著者 | Nakashima, C, Li, J, Arakawa, T, Yamada, C, Ishiwata, A, Fujita, K, Fushinobu, S. | 登録日 | 2022-11-17 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Identification and characterization of endo-alpha-, exo-alpha-, and exo-beta-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria. Nat Commun, 14, 2023
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7XWA
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![BU of 7xwa by Molmil](/molmil-images/mine/7xwa) | Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron BA.4/5 variant spike protein in complex with its receptor ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Suzuki, T, Kimura, K, Hashiguchi, T. | 登録日 | 2022-05-26 | 公開日 | 2022-09-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5. Cell, 185, 2022
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7YTB
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![BU of 7ytb by Molmil](/molmil-images/mine/7ytb) | Crystal structure of Kin4B8 | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Kin4B8, RETINAL | 著者 | Murakoshi, S, Chazan, A, Shihoya, W, Beja, O, Nureki, O. | 登録日 | 2022-08-14 | 公開日 | 2023-03-15 | 最終更新日 | 2023-03-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Phototrophy by antenna-containing rhodopsin pumps in aquatic environments. Nature, 615, 2023
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8X8S
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![BU of 8x8s by Molmil](/molmil-images/mine/8x8s) | Crystal structure of Cypovirus Polyhedra mutant fused with c-Myc fragment | 分子名称: | Polyhedrin,Myc proto-oncogene protein | 著者 | Kojima, M, Ueno, T, Abe, S, Hirata, K. | 登録日 | 2023-11-28 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proc.Natl.Acad.Sci.USA, 121, 2024
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8WLG
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![BU of 8wlg by Molmil](/molmil-images/mine/8wlg) | Crystal structure of Cypovirus Polyhedra mutant fused with c-Myc fragment | 分子名称: | Polyhedrin,Myc proto-oncogene protein | 著者 | Kojima, M, Ueno, T, Abe, S, Hirata, K. | 登録日 | 2023-09-29 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proc.Natl.Acad.Sci.USA, 121, 2024
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8X8V
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![BU of 8x8v by Molmil](/molmil-images/mine/8x8v) | Crystal structure of Cypovirus Polyhedra mutant fused with c-Myc fragment | 分子名称: | Polyhedrin,Myc proto-oncogene protein | 著者 | Kojima, M, Ueno, T, Abe, S, Hirata, K. | 登録日 | 2023-11-29 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proc.Natl.Acad.Sci.USA, 121, 2024
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5H35
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![BU of 5h35 by Molmil](/molmil-images/mine/5h35) | Crystal structures of the TRIC trimeric intracellular cation channel orthologue from Sulfolobus solfataricus | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Fab Heavy Chain, Fab Light Chain, ... | 著者 | Kasuya, G, Hiraizumi, M, Hattori, M, Nureki, O. | 登録日 | 2016-10-20 | 公開日 | 2017-01-11 | 最終更新日 | 2020-02-26 | 実験手法 | X-RAY DIFFRACTION (2.642 Å) | 主引用文献 | Crystal structures of the TRIC trimeric intracellular cation channel orthologues Cell Res., 26, 2016
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8J2Q
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![BU of 8j2q by Molmil](/molmil-images/mine/8j2q) | Crystal structure of Cypovirus Polyhedra mutant fused with c-Myc fragment | 分子名称: | Polyhedrin,Myc proto-oncogene protein | 著者 | Kojima, M, Ueno, T, Abe, S, Hirata, K. | 登録日 | 2023-04-15 | 公開日 | 2024-04-17 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proc.Natl.Acad.Sci.USA, 121, 2024
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4UDB
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![BU of 4udb by Molmil](/molmil-images/mine/4udb) | MR in complex with desisobutyrylciclesonide | 分子名称: | DESISOBUYTYRYL CICLESONIDE, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Edman, K, Hogner, A, Hussein, A, Aagaard, A, Backstrom, S, Bodin, C, Wissler, L, JellesmarkJensen, T, Cavallin, A, Nilsson, E, Lepisto, M, Guallar, V. | 登録日 | 2014-12-09 | 公開日 | 2015-11-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Ligand Binding Mechanism in Steroid Receptors: From Conserved Plasticity to Differential Evolutionary Constraints. Structure, 23, 2015
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