Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in 17beta-estradiol-bound form

This is a large structure.

Summary for 6KEO

DescriptorGlutathione S-transferase E14, ESTRADIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywordsglutathione, glutathione s-transferase, gst, transferase
Biological sourceDrosophila melanogaster (Fruit fly)
Total number of polymer chains2
Total molecular weight55754.44
Koiwai, K.,Inaba, K.,Morohashi, K.,Yumoto, F.,Niwa, R.,Senda, T. (deposition date: 2019-07-04, release date: 2019-10-02)
Primary citation
Koiwai, K.,Inaba, K.,Morohashi, K.,Enya, S.,Arai, R.,Kojima, H.,Okabe, T.,Fujikawa, Y.,Inoue, H.,Yoshino, R.,Hirokawa, T.,Kato, K.,Fukuzawa, K.,Nakamura, A.,Nagano, T.,Yumoto, F.,Senda, T.,Niwa, R.
Integrative in silico, in vitro, and in vivo approach unravels an essential amino acid for the function of the insect steroidgenic regulator.
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2097 0.2% 1.0% 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution