6YPE

Crystal structure of the human neuronal pentraxin 1 (NP1) pentraxin (PTX) domain.

Summary for 6YPE

Entry DOI	10.2210/pdb6ype/pdb
Descriptor	Neuronal pentraxin-1, CALCIUM ION, CACODYLATE ION, ... (4 entities in total)
Functional Keywords	cell adhesion, synapse formation, ampa receptor
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	45833.70
Authors	Elegheert, J.,Clayton, A.J.,Aricescu, A.R. (deposition date: 2020-04-15, release date: 2020-06-03, Last modification date: 2024-01-24)
Primary citation	Suzuki, K.,Elegheert, J.,Song, I.,Sasakura, H.,Senkov, O.,Matsuda, K.,Kakegawa, W.,Clayton, A.J.,Chang, V.T.,Ferrer-Ferrer, M.,Miura, E.,Kaushik, R.,Ikeno, M.,Morioka, Y.,Takeuchi, Y.,Shimada, T.,Otsuka, S.,Stoyanov, S.,Watanabe, M.,Takeuchi, K.,Dityatev, A.,Aricescu, A.R.,Yuzaki, M. A synthetic synaptic organizer protein restores glutamatergic neuronal circuits. Science, 369:-, 2020 Cited by PubMed: 32855309 DOI: 10.1126/science.abb4853 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation