6KEP

Crystal structure of Drosophila melanogaster Noppera-bo, glutathione S-transferase epsilon 14 (DmGSTE14), in 17beta-estradiol- and glutathione-bound form

This is a large structure.

Summary for 6KEP

DescriptorGlutathione S-transferase E14, GLUTATHIONE, ESTRADIOL, ... (4 entities in total)
Functional Keywordsglutathione, glutathione s-transferase, gst, transferase
Biological sourceDrosophila melanogaster (Fruit fly)
Total number of polymer chains2
Total molecular weight56246.94
Authors
Koiwai, K.,Inaba, K.,Morohashi, K.,Yumoto, F.,Niwa, R.,Senda, T. (deposition date: 2019-07-04, release date: 2019-10-02, Last modification date: 2020-05-27)
Primary citation
Koiwai, K.,Inaba, K.,Morohashi, K.,Enya, S.,Arai, R.,Kojima, H.,Okabe, T.,Fujikawa, Y.,Inoue, H.,Yoshino, R.,Hirokawa, T.,Kato, K.,Fukuzawa, K.,Shimada-Niwa, Y.,Nakamura, A.,Yumoto, F.,Senda, T.,Niwa, R.
An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo.
J.Biol.Chem., 295:7154-7167, 2020
PubMed: 32241910 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.RA119.011463
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.55 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.18220 0.2% 0.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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168889
PDB entries from 2020-09-16