7XWA

Crystal structure of the receptor binding domain of SARS-CoV-2 Omicron BA.4/5 variant spike protein in complex with its receptor ACE2

Summary for 7XWA

• Entry DOI: 10.2210/pdb7xwa/pdb
• Descriptor: Processed angiotensin-converting enzyme 2, Spike protein S1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: spike protein, receptor, coronavirus, viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 199034.57

Authors

Suzuki, T.,Kimura, K.,Hashiguchi, T. (deposition date: 2022-05-26, release date: 2022-09-28, Last modification date: 2023-11-29)

• Primary citation: Kimura, I.,Yamasoba, D.,Tamura, T.,Nao, N.,Suzuki, T.,Oda, Y.,Mitoma, S.,Ito, J.,Nasser, H.,Zahradnik, J.,Uriu, K.,Fujita, S.,Kosugi, Y.,Wang, L.,Tsuda, M.,Kishimoto, M.,Ito, H.,Suzuki, R.,Shimizu, R.,Begum, M.M.,Yoshimatsu, K.,Kimura, K.T.,Sasaki, J.,Sasaki-Tabata, K.,Yamamoto, Y.,Nagamoto, T.,Kanamune, J.,Kobiyama, K.,Asakura, H.,Nagashima, M.,Sadamasu, K.,Yoshimura, K.,Shirakawa, K.,Takaori-Kondo, A.,Kuramochi, J.,Schreiber, G.,Ishii, K.J.,Hashiguchi, T.,Ikeda, T.,Saito, A.,Fukuhara, T.,Tanaka, S.,Matsuno, K.,Sato, K.; Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5.; Cell, 185:3992-, 2022; PubMed: 36198317; DOI: 10.1016/j.cell.2022.09.018

Experimental method

X-RAY DIFFRACTION (3.36 Å)