8K8Z
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![BU of 8k8z by Molmil](/molmil-images/mine/8k8z) | CryoEM structure of LonC protease hexamer in presence of AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K92
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![BU of 8k92 by Molmil](/molmil-images/mine/8k92) | CryoEM structure of LonC S582A hexamer with Lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.31 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K95
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![BU of 8k95 by Molmil](/molmil-images/mine/8k95) | CryoEM structure of LonC protease open Hexamer, AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K91
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![BU of 8k91 by Molmil](/molmil-images/mine/8k91) | CryoEM structure of LonC S582A hepatmer with Lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K93
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![BU of 8k93 by Molmil](/molmil-images/mine/8k93) | CryoEM structure of LonC protease S582A open hexamer with lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8Y
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![BU of 8k8y by Molmil](/molmil-images/mine/8k8y) | CryoEM structure of LonC heptamer in presence of AGS | 分子名称: | Monothiophosphate, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8W
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![BU of 8k8w by Molmil](/molmil-images/mine/8k8w) | CryoEM structure of LonC protease open hexamer, apo state | 分子名称: | endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K96
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![BU of 8k96 by Molmil](/molmil-images/mine/8k96) | CryoEM structure of LonC protease hepatmer with Bortezomib | 分子名称: | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, PHOSPHATE ION, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K97
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![BU of 8k97 by Molmil](/molmil-images/mine/8k97) | CryoEM structure of LonC protease hexamer with Bortezomib | 分子名称: | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, PHOSPHATE ION, endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K8X
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![BU of 8k8x by Molmil](/molmil-images/mine/8k8x) | CryoEM of LonC open pentamer, apo state | 分子名称: | endopeptidase La | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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8K94
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![BU of 8k94 by Molmil](/molmil-images/mine/8k94) | CryoEM structure of LonC protease S582A open pentamer with lysozyme | 分子名称: | Endopeptidase La, Monothiophosphate | 著者 | Li, M, Hsieh, K, Liu, H, Zhang, S, Gao, Y, Gong, Q, Zhang, K, Chang, C, Li, S. | 登録日 | 2023-07-31 | 公開日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Bifurcated assembly pathway and dual function of a Lon-like protease revealed by cryo-EM Analysis Fundam Res, 2024
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5W96
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![BU of 5w96 by Molmil](/molmil-images/mine/5w96) | Solution structure of phage derived peptide inhibitor of frizzled 7 receptor | 分子名称: | Fz7 binding peptide | 著者 | Nile, A.H, de Sousa e Melo, F, Mukund, S, Piskol, R, Hansen, S, Zhou, L, Zhang, Y, Fu, Y, Gogol, E.B, Komuves, L.G, Modrusan, Z, Angers, S, Franke, Y, Koth, C, Fairbrother, W.J, Wang, W, de Sauvage, F.J, Hannoush, R.N. | 登録日 | 2017-06-22 | 公開日 | 2018-04-18 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A selective peptide inhibitor of Frizzled 7 receptors disrupts intestinal stem cells. Nat. Chem. Biol., 14, 2018
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6VGI
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![BU of 6vgi by Molmil](/molmil-images/mine/6vgi) | Crystal Structures of FLAP bound to MK-866 | 分子名称: | 3-[3-(tert-butylsulfanyl)-1-[(4-chlorophenyl)methyl]-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid, 5-lipoxygenase-activating protein, SULFATE ION | 著者 | Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H. | 登録日 | 2020-01-08 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP). Biochim Biophys Acta Gen Subj, 1865, 2020
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3G12
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![BU of 3g12 by Molmil](/molmil-images/mine/3g12) | Crystal structure of a putative lactoylglutathione lyase from Bdellovibrio bacteriovorus | 分子名称: | Putative lactoylglutathione lyase, SULFATE ION | 著者 | Patskovsky, Y, Madegowda, M, Gilmore, M, Chang, S, Maletic, M, Smith, D, Sauder, J.M, Burley, S.K, Swaminathan, S, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-01-29 | 公開日 | 2009-02-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Crystal structure of a putative lactoylglutathione lyase from Bdellovibrio bacteriovorus To be Published
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6VGC
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![BU of 6vgc by Molmil](/molmil-images/mine/6vgc) | Crystal Structures of FLAP bound to DG-031 | 分子名称: | (2R)-cyclopentyl{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid, 5-lipoxygenase-activating protein, CALCIUM ION, ... | 著者 | Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H. | 登録日 | 2020-01-07 | 公開日 | 2020-12-02 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP). Biochim Biophys Acta Gen Subj, 1865, 2020
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6VL4
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![BU of 6vl4 by Molmil](/molmil-images/mine/6vl4) | Crystal Structure of mPGES-1 bound to DG-031 | 分子名称: | (2R)-cyclopentyl{4-[(quinolin-2-yl)methoxy]phenyl}acetic acid, Prostaglandin E synthase, TETRAETHYLENE GLYCOL, ... | 著者 | Ho, J.D, Lee, M.R, Rauch, C.T, Aznavour, K, Park, J.S, Luz, J.G, Antonysamy, S, Condon, B, Maletic, M, Zhang, A, Hickey, M.J, Hughes, N.E, Chandrasekhar, S, Sloan, A.V, Gooding, K, Harvey, A, Yu, X.P, Kahl, S.D, Norman, B.H. | 登録日 | 2020-01-22 | 公開日 | 2020-12-02 | 最終更新日 | 2020-12-16 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure-based, multi-targeted drug discovery approach to eicosanoid inhibition: Dual inhibitors of mPGES-1 and 5-lipoxygenase activating protein (FLAP). Biochim Biophys Acta Gen Subj, 1865, 2020
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8HSY
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![BU of 8hsy by Molmil](/molmil-images/mine/8hsy) | Acyl-ACP Synthetase structure | 分子名称: | Acyl-acyl carrier protein synthetase | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2022-12-20 | 公開日 | 2023-12-27 | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | 主引用文献 | Acyl-ACP Synthetase structure To Be Published
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2QJC
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![BU of 2qjc by Molmil](/molmil-images/mine/2qjc) | Crystal structure of a putative diadenosine tetraphosphatase | 分子名称: | Diadenosine tetraphosphatase, putative, MANGANESE (II) ION, ... | 著者 | Sugadev, R, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2007-07-06 | 公開日 | 2007-07-24 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural genomics of protein phosphatases. J.Struct.Funct.Genom., 8, 2007
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7BV2
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![BU of 7bv2 by Molmil](/molmil-images/mine/7bv2) | The nsp12-nsp7-nsp8 complex bound to the template-primer RNA and triphosphate form of Remdesivir(RTP) | 分子名称: | MAGNESIUM ION, Non-structural protein 7, Non-structural protein 8, ... | 著者 | Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. | 登録日 | 2020-04-09 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020
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7BV1
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![BU of 7bv1 by Molmil](/molmil-images/mine/7bv1) | Cryo-EM structure of the apo nsp12-nsp7-nsp8 complex | 分子名称: | Non-structural protein 7, Non-structural protein 8, RNA-directed RNA polymerase, ... | 著者 | Yin, W, Mao, C, Luan, X, Shen, D, Shen, Q, Su, H, Wang, X, Zhou, F, Zhao, W, Gao, M, Chang, S, Xie, Y.C, Tian, G, Jiang, H.W, Tao, S.C, Shen, J, Jiang, Y, Jiang, H, Xu, Y, Zhang, S, Zhang, Y, Xu, H.E. | 登録日 | 2020-04-09 | 公開日 | 2020-04-22 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir. Science, 368, 2020
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8FN0
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![BU of 8fn0 by Molmil](/molmil-images/mine/8fn0) | CryoEM structure of Go-coupled NTSR1 with a biased allosteric modulator | 分子名称: | 2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Krumm, B.E, DiBerto, J.F, Olsen, R.H.J, Kang, H, Slocum, S.T, Zhang, S, Strachan, R.T, Fay, J.F, Roth, B.L. | 登録日 | 2022-12-26 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry, 62, 2023
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8FMZ
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![BU of 8fmz by Molmil](/molmil-images/mine/8fmz) | Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, MiniGq, ... | 著者 | Krumm, B.E, Diberto, J.F, Olsen, R.H.J, Kang, H, Slocum, S.T, Zhang, S, Strachan, R.T, Fay, J.F, Roth, B.L. | 登録日 | 2022-12-26 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | 主引用文献 | Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry, 62, 2023
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8FN1
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![BU of 8fn1 by Molmil](/molmil-images/mine/8fn1) | CryoEM structure of Go-coupled NTSR1 | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(o) subunit alpha, ... | 著者 | Krumm, B.E, DiBerto, J.F, Olsen, R.H.J, Kang, H, Slocum, S.T, Zhang, S, Strachan, R.T, Fay, J.F, Roth, B.L. | 登録日 | 2022-12-26 | 公開日 | 2023-03-29 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Neurotensin Receptor Allosterism Revealed in Complex with a Biased Allosteric Modulator. Biochemistry, 62, 2023
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3EVZ
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8I22
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![BU of 8i22 by Molmil](/molmil-images/mine/8i22) | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester | 分子名称: | 7-ethoxy-7-oxidanylidene-heptanoic acid, Acyl-acyl carrier protein synthetase | 著者 | Huang, H, Wang, C, Chang, S, Cui, T, Xu, Y, Zhang, H, Zhou, C, Zhang, X, Feng, Y. | 登録日 | 2023-01-13 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.15 Å) | 主引用文献 | Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester To Be Published
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