8I22

Acyl-ACP synthetase structure bound to pimelic acid monoethyl ester

Summary for 8I22

Entry DOI	10.2210/pdb8i22/pdb
EMDB information	35129
Descriptor	Acyl-acyl carrier protein synthetase, 7-ethoxy-7-oxidanylidene-heptanoic acid (2 entities in total)
Functional Keywords	acyl-acp synthetase, tool enzyme, cytosolic protein
Biological source	Vibrio harveyi
Total number of polymer chains	6
Total formula weight	364106.87
Authors	Huang, H.,Wang, C.,Chang, S.,Cui, T.,Xu, Y.,Zhang, H.,Zhou, C.,Zhang, X.,Feng, Y. (deposition date: 2023-01-13, release date: 2024-01-17, Last modification date: 2025-07-02)
Primary citation	Huang, H.,Wang, C.,Chang, S.,Cui, T.,Xu, Y.,Zhang, H.,Zhou, C.,Zhang, X.,Feng, Y. Structure and catalytic mechanism of exogenous fatty acid recycling by AasS, a versatile acyl-ACP synthetase Nat.Struct.Mol.Biol., 2025 Cited by DOI: 10.1038/s41594-024-01464-7 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.15 Å)

Structure validation