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7CP1
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BU of 7cp1 by Molmil
Crystal structure of isocitrate lyase in complex with succinate and itaconate
分子名称: 2-methylidenebutanedioic acid, Isocitrate lyase, MAGNESIUM ION, ...
著者Kwon, S, Park, H.H.
登録日2020-08-05
公開日2021-05-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Heterogeneous multimeric structure of isocitrate lyase in complex with succinate and itaconate provides novel insights into its inhibitory mechanism.
Plos One, 16, 2021
4TXY
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BU of 4txy by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog
分子名称: Cyclic AMP-GMP synthase, MAGNESIUM ION
著者Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
登録日2014-07-07
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.0001 Å)
主引用文献Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
4TY0
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BU of 4ty0 by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with linear intermediate 5' pppA(3',5')pG
分子名称: ACETATE ION, Cyclic AMP-GMP synthase, MAGNESIUM ION, ...
著者Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
登録日2014-07-07
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
4TXZ
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BU of 4txz by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP
分子名称: Cyclic AMP-GMP synthase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
登録日2014-07-07
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
9ARD
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BU of 9ard by Molmil
Structure of Pycsar EcPycC cyclase immunoglobulin-like AGS-C domain
分子名称: Cytidylate cyclase
著者Richmond-Buccola, D, Kranzusch, P.J.
登録日2024-02-23
公開日2024-06-19
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献A large-scale type I CBASS antiphage screen identifies the phage prohead protease as a key determinant of immune activation and evasion.
Cell Host Microbe, 32, 2024
5K4C
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BU of 5k4c by Molmil
Structure of eukaryotic translation initiation factor 3 subunit D (eIF3d) cap binding domain from Nasonia vitripennis, Crystal form 2
分子名称: Eukaryotic translation initiation factor 3 subunit D, GLYCEROL
著者Kranzusch, P.J, Lee, A.S.Y, Doudna, J.A, Cate, J.H.D.
登録日2016-05-20
公開日2016-07-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation.
Nature, 536, 2016
4KM5
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BU of 4km5 by Molmil
X-ray crystal structure of human cyclic GMP-AMP synthase (cGAS)
分子名称: Cyclic GMP-AMP synthase, ZINC ION
著者Kranzusch, P.J, Lee, A.S.Y, Berger, J.M, Doudna, J.A.
登録日2013-05-08
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity.
Cell Rep, 3, 2013
5CFP
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BU of 5cfp by Molmil
Crystal structure of anemone STING (Nematostella vectensis) 'humanized' F276K in complex with 3', 3' c-di-GMP, c[G(3', 5')pG(3', 5')p]'
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Stimulator of Interferon Genes
著者Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E.
登録日2015-07-08
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.066 Å)
主引用文献Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
5CFO
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BU of 5cfo by Molmil
Crystal structure of anemone STING (Nematostella vectensis) in apo 'rotated' open conformation
分子名称: Stimulator of Interferon Genes
著者Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E.
登録日2015-07-08
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
5CFL
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BU of 5cfl by Molmil
Crystal structure of anemone STING (Nematostella vectensis) in complex with 3', 3' c-di-GMP, c[G(3', 5')pG(3', 5')p]
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CITRATE ANION, Stimulator of Interferon Genes
著者Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E.
登録日2015-07-08
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.836 Å)
主引用文献Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
5CFR
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BU of 5cfr by Molmil
Crystal structure of anemone STING (Nematostella vectensis) in apo 'unrotated' closed conformation
分子名称: CALCIUM ION, Stimulator of Interferon Genes
著者Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E.
登録日2015-07-08
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
5CFN
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BU of 5cfn by Molmil
Crystal structure of anemone STING (Nematostella vectensis) in complex with 3',3' c-di-AMP, c[A(3',5')pA(3',5')p]
分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Stimulator of Interferon Genes
著者Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E.
登録日2015-07-08
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
5CFQ
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BU of 5cfq by Molmil
Crystal structure of anemone STING (Nematostella vectensis) in complex with 2',3' cGAMP, c[G(2',5')pA(3',5')p]
分子名称: SULFATE ION, Stimulator of Interferon Genes, cGAMP
著者Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E.
登録日2015-07-08
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
5CFM
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BU of 5cfm by Molmil
Crystal structure of anemone STING (Nematostella vectensis) in complex with 3', 3' cGAMP, c[G(3', 5')pA(3', 5')p]
分子名称: 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, CITRATE ANION, Stimulator of Interferon Genes
著者Kranzusch, P.J, Wilson, S.C, Lee, A.S.Y, Berger, J.M, Doudna, J.A, Vance, R.E.
登録日2015-07-08
公開日2015-08-26
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.994 Å)
主引用文献Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling.
Mol.Cell, 59, 2015
7LT2
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BU of 7lt2 by Molmil
Structure of a dsRNA-sensing cGAS-like receptor from the beetle Tribolium castaneum
分子名称: MANGANESE (II) ION, Mab-21 domain-containing protein
著者Slavik, K.M, Morehouse, B.R, Kranzusch, P.J.
登録日2021-02-18
公開日2021-07-21
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7LT1
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BU of 7lt1 by Molmil
Structure of the cGAS-like receptor human MB21D2
分子名称: Protein MB21D2, SULFATE ION
著者Morehouse, B.R, Slavik, K.M, Kranzusch, P.J.
登録日2021-02-18
公開日2021-07-21
最終更新日2021-09-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7MWY
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BU of 7mwy by Molmil
Structure of the drosophila STING cyclic dinucleotide binding domain
分子名称: STING
著者Slavik, K.M, Ragucci, A.E, Kranzusch, P.J.
登録日2021-05-17
公開日2021-07-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021
7MWZ
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BU of 7mwz by Molmil
Structure of drosophila STING in complex with 3'2'-cGAMP
分子名称: 3'2'-cGAMP, STING
著者Slavik, K.M, Ragucci, A.E, Kranzusch, P.J.
登録日2021-05-17
公開日2021-07-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.
Nature, 597, 2021

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