7CP1
Crystal structure of isocitrate lyase in complex with succinate and itaconate
Summary for 7CP1
Entry DOI | 10.2210/pdb7cp1/pdb |
Descriptor | Isocitrate lyase, SUCCINIC ACID, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | glyoxylate cycle, isocitrate lyase, succinate, itaconate, mycobacterium tuberculosis, lyase |
Biological source | Mycobacterium tuberculosis H37Rv |
Total number of polymer chains | 2 |
Total formula weight | 96707.86 |
Authors | Kwon, S.,Park, H.H. (deposition date: 2020-08-05, release date: 2021-05-19, Last modification date: 2023-11-29) |
Primary citation | Kwon, S.,Chun, H.L.,Ha, H.J.,Lee, S.Y.,Park, H.H. Heterogeneous multimeric structure of isocitrate lyase in complex with succinate and itaconate provides novel insights into its inhibitory mechanism. Plos One, 16:e0251067-e0251067, 2021 Cited by PubMed: 33951112DOI: 10.1371/journal.pone.0251067 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.58 Å) |
Structure validation
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