7MWZ

Structure of drosophila STING in complex with 3'2'-cGAMP

Summary for 7MWZ

• Entry DOI: 10.2210/pdb7mwz/pdb
• Descriptor: STING, 3'2'-cGAMP (3 entities in total)
• Functional Keywords: sting, cyclic dinucleotide receptor, immune system
• Biological source: Drosophila eugracilis
• Total number of polymer chains: 4
• Total formula weight: 164953.10

Authors

Slavik, K.M.,Ragucci, A.E.,Kranzusch, P.J. (deposition date: 2021-05-17, release date: 2021-07-21, Last modification date: 2024-04-03)

• Primary citation: Slavik, K.M.,Morehouse, B.R.,Ragucci, A.E.,Zhou, W.,Ai, X.,Chen, Y.,Li, L.,Wei, Z.,Bahre, H.,Konig, M.,Seifert, R.,Lee, A.S.Y.,Cai, H.,Imler, J.L.,Kranzusch, P.J.; cGAS-like receptors sense RNA and control 3'2'-cGAMP signalling in Drosophila.; Nature, 597:109-113, 2021; PubMed: 34261127; DOI: 10.1038/s41586-021-03743-5

Experimental method

X-RAY DIFFRACTION (2 Å)