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7MWZ

Structure of drosophila STING in complex with 3'2'-cGAMP

Functional Information from GO Data
ChainGOidnamespacecontents
A0002218biological_processactivation of innate immune response
A0003796molecular_functionlysozyme activity
A0009253biological_processpeptidoglycan catabolic process
A0016798molecular_functionhydrolase activity, acting on glycosyl bonds
A0016998biological_processcell wall macromolecule catabolic process
A0030430cellular_componenthost cell cytoplasm
A0031640biological_processkilling of cells of another organism
A0032481biological_processpositive regulation of type I interferon production
A0035438molecular_functioncyclic-di-GMP binding
A0042742biological_processdefense response to bacterium
A0044659biological_processviral release from host cell by cytolysis
B0002218biological_processactivation of innate immune response
B0003796molecular_functionlysozyme activity
B0009253biological_processpeptidoglycan catabolic process
B0016798molecular_functionhydrolase activity, acting on glycosyl bonds
B0016998biological_processcell wall macromolecule catabolic process
B0030430cellular_componenthost cell cytoplasm
B0031640biological_processkilling of cells of another organism
B0032481biological_processpositive regulation of type I interferon production
B0035438molecular_functioncyclic-di-GMP binding
B0042742biological_processdefense response to bacterium
B0044659biological_processviral release from host cell by cytolysis
C0002218biological_processactivation of innate immune response
C0003796molecular_functionlysozyme activity
C0009253biological_processpeptidoglycan catabolic process
C0016798molecular_functionhydrolase activity, acting on glycosyl bonds
C0016998biological_processcell wall macromolecule catabolic process
C0030430cellular_componenthost cell cytoplasm
C0031640biological_processkilling of cells of another organism
C0032481biological_processpositive regulation of type I interferon production
C0035438molecular_functioncyclic-di-GMP binding
C0042742biological_processdefense response to bacterium
C0044659biological_processviral release from host cell by cytolysis
D0002218biological_processactivation of innate immune response
D0003796molecular_functionlysozyme activity
D0009253biological_processpeptidoglycan catabolic process
D0016798molecular_functionhydrolase activity, acting on glycosyl bonds
D0016998biological_processcell wall macromolecule catabolic process
D0030430cellular_componenthost cell cytoplasm
D0031640biological_processkilling of cells of another organism
D0032481biological_processpositive regulation of type I interferon production
D0035438molecular_functioncyclic-di-GMP binding
D0042742biological_processdefense response to bacterium
D0044659biological_processviral release from host cell by cytolysis
Functional Information from PDB Data
site_idAC1
Number of Residues26
Detailsbinding site for residue 4UR B 401
ChainResidue
AASN159
BASN159
BTYR160
BTYR164
BARG234
BPRO235
BPHE236
BLYS237
BGLU257
BTHR260
BPRO261
ATYR160
BSER264
BHOH522
BHOH524
BHOH528
BHOH531
BHOH549
BHOH565
ATYR164
AVAL232
AARG234
APHE236
ATHR260
AHOH447
AHOH464

site_idAC2
Number of Residues25
Detailsbinding site for residue 4UR C 401
ChainResidue
CASN159
CTYR160
CTYR164
CARG234
CPRO235
CPHE236
CLYS237
CGLU257
CTHR260
CPRO261
CSER264
CHOH515
CHOH523
CHOH528
CHOH535
CHOH538
CHOH551
DASN159
DTYR160
DTYR164
DARG234
DTHR260
DPRO261
DSER264
DHOH446

219869

PDB entries from 2024-05-15

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