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Cryo-EM structure of prefusion SARS-CoV-2 spike glycoprotein in complex with 910-30 Fab
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 910-30 Fab heavy chain, ...
著者	Cerutti, G, Shapiro, L.
登録日	2020-11-21
公開日	2021-02-10
最終更新日	2022-11-09
実験手法	ELECTRON MICROSCOPY (4.75 Å)
主引用文献	Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses. Cell Rep, 37, 2021

7LAB

Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1052
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1052 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-06
公開日	2021-03-10
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (2.97 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7LAA

Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1041
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1041 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-06
公開日	2021-03-17
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.42 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7LS9

Cryo-EM structure of neutralizing antibody 1-57 in complex with prefusion SARS-CoV-2 spike glycoprotein
分子名称:	1-57 Fab heavy chain, 1-57 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Cerutti, G, Shapiro, L.
登録日	2021-02-17
公開日	2021-03-17
最終更新日	2021-09-29
実験手法	ELECTRON MICROSCOPY (3.42 Å)
主引用文献	Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies. Structure, 29, 2021

7LSS

Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-7
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2-7 variable heavy chain, ...
著者	Rapp, M, Shapiro, L.
登録日	2021-02-18
公開日	2021-03-17
最終更新日	2021-09-29
実験手法	ELECTRON MICROSCOPY (3.72 Å)
主引用文献	Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies. Structure, 29, 2021

7LD1

Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-12
公開日	2021-01-27
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.4 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

7LCN

Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1050.1
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1050.1 heavy chain, ...
著者	Manne, K, Acharya, P.
登録日	2021-01-11
公開日	2021-01-27
最終更新日	2021-08-18
実験手法	ELECTRON MICROSCOPY (3.35 Å)
主引用文献	In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell, 184, 2021

6UDA

Cryo-EM structure of CH235UCA bound to Man5-enriched CH505.N279K.G458Y.SOSIP.664
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CH235 UCA heavy chain Fab, CH235 UCA light chain Fab, ...
著者	Henderson, R, Acharya, P.
登録日	2019-09-19
公開日	2019-10-02
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (4.2 Å)
主引用文献	Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancester of CH235 lineage CD4bs broadly neutralizing antibodies. Plos Pathog., 15, 2019

6VPX

Nanodisc of full-length HIV-1 Envelope glycoprotein clone AMC011 in complex with one PGT151 Fab and three 10E8 Fabs
分子名称:	(2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Rantalainen, K, Ward, A.B.W.
登録日	2020-02-04
公開日	2020-04-22
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (5 Å)
主引用文献	HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies. Cell Rep, 31, 2020

6VTU

DH717.1 Fab monomer in complex with man9 glycan
分子名称:	DH717.1 heavy chain, DH717.1 light chain, GLYCEROL, ...
著者	Fera, D, Bronkema, N.
登録日	2020-02-13
公開日	2020-12-30
最終更新日	2023-10-11
実験手法	X-RAY DIFFRACTION (2.61 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

6B5M

Structure of PfCSP peptide 21 with human protective antibody CIS43
分子名称:	1,2-ETHANEDIOL, CIS43 Fab Heavy chain, CIS43 Fab Light chain, ...
著者	Pancera, M, Weidle, C.
登録日	2017-09-29
公開日	2018-03-21
最終更新日	2018-04-25
実験手法	X-RAY DIFFRACTION (1.79 Å)
主引用文献	A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018

6B5T

Structure of PfCSP peptide 29 with human antibody CIS42
分子名称:	AMMONIUM ION, CIS42 Fab Heavy chain, CIS42 Fab Light chain, ...
著者	Pancera, M, Weidle, C.
登録日	2017-09-29
公開日	2018-03-21
最終更新日	2018-04-25
実験手法	X-RAY DIFFRACTION (2.222 Å)
主引用文献	A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018

6B5N

Structure of PfCSP peptide 25 with human protective antibody CIS43
分子名称:	CIS43 Fab Heavy chain, CIS43 Fab Light chain, pfCSP peptide 25: ASN-VAL-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP
著者	Pancera, M, Weidle, C.
登録日	2017-09-29
公開日	2018-03-21
最終更新日	2018-04-25
実験手法	X-RAY DIFFRACTION (1.98 Å)
主引用文献	A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018

6B5O

Structure of PfCSP peptide 29 with human protective antibody CIS43
分子名称:	CIS43 Fab Heavy chain, CIS43 Fab Light chain, PfCSP peptide 29: ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-ASN
著者	Pancera, M, Weidle, C.
登録日	2017-09-29
公開日	2018-03-21
最終更新日	2018-04-25
実験手法	X-RAY DIFFRACTION (2.194 Å)
主引用文献	A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018

6B5L

Structure of PfCSP peptide 20 with human protective antibody CIS43
分子名称:	CIS43 Fab Heavy chain, CIS43 Fab Light Chain, PfCSP peptide 20: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL
著者	Pancera, M, Weidle, C.
登録日	2017-09-29
公開日	2018-03-21
最終更新日	2018-04-25
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018

6B5S

Structure of PfCSP peptide 25 with human antibody CIS42
分子名称:	AMMONIUM ION, CIS42 Fab Heavy chain, CIS42 Fab Light chain, ...
著者	Pancera, M, Weidle, C.
登録日	2017-09-29
公開日	2018-03-21
最終更新日	2019-01-09
実験手法	X-RAY DIFFRACTION (1.983 Å)
主引用文献	A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018

6C6Z

Crystal structure of potent neutralizing antibody CDC2-C2 in complex with MERS-CoV S1 RBD
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CDC2-C2 heavy chain, Antibody CDC2-C2 light chain, ...
著者	Wang, N, McLellan, J.S.
登録日	2018-01-19
公開日	2018-01-31
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape. J. Virol., 92, 2018

6B5R

Structure of PfCSP peptide 21 with human antibody CIS42
分子名称:	CIS42 Fab Heavy chain, CIS42 Fab Light chain, PfCSP peptide 21: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP-PRO-ASN
著者	Pancera, M, Weidle, C.
登録日	2017-09-29
公開日	2018-03-21
最終更新日	2018-04-25
実験手法	X-RAY DIFFRACTION (1.775 Å)
主引用文献	A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018

6B5P

Structure of PfCSP peptide 20 with human antibody CIS42
分子名称:	CIS42 Fab Heavy chain, CIS42 Fab Light chain, pfCSP peptide 20: ASN-PRO-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP
著者	Pancera, M, Weidle, C.
登録日	2017-09-29
公開日	2018-03-21
最終更新日	2018-04-25
実験手法	X-RAY DIFFRACTION (2.297 Å)
主引用文献	A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018

7L6M

Cryo-EM structure of DH898.1 Fab-dimer from local refinement of the Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer
分子名称:	DH898.1 Fab heavy chain, DH898.1 Fab light chain
著者	Manne, K, Edwards, R.J, Acharya, P.
登録日	2020-12-23
公開日	2021-02-10
最終更新日	2021-06-09
実験手法	ELECTRON MICROSCOPY (4.7 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7L2C

Crystallographic structure of neutralizing antibody 2-51 in complex with SARS-CoV-2 spike N-terminal domain (NTD)
分子名称:	2-51 heavy chain, 2-51 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Cerutti, G, Reddem, E.R, Shapiro, L.
登録日	2020-12-16
公開日	2021-02-10
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (3.65 Å)
主引用文献	Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe, 29, 2021

7L02

Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to one copy of domain-swapped antibody 2G12
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ...
著者	Manne, K, Henderson, R, Acharya, P.
登録日	2020-12-10
公開日	2020-12-30
最終更新日	2021-06-09
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7L09

Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound domain-swapped antibody 2G12 from masked 3D refinement
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 heavy chain, ...
著者	Manne, K, Henderson, R, Acharya, P.
登録日	2020-12-11
公開日	2020-12-30
最終更新日	2021-06-09
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell, 184, 2021

7L2E

Cryo-EM structure of NTD-directed neutralizing antibody 4-18 in complex with prefusion SARS-CoV-2 spike glycoprotein
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-18 heavy chain, ...
著者	Cerutti, G, Shapiro, L.
登録日	2020-12-16
公開日	2021-03-24
最終更新日	2021-05-26
実験手法	ELECTRON MICROSCOPY (2.97 Å)
主引用文献	Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe, 29, 2021

7L2F

Cryo-EM structure of NTD-directed neutralizing antibody 5-24 in complex with prefusion SARS-CoV-2 spike glycoprotein
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-24 heavy chain, ...
著者	Cerutti, G, Shapiro, L.
登録日	2020-12-16
公開日	2021-03-24
最終更新日	2021-05-26
実験手法	ELECTRON MICROSCOPY (3.9 Å)
主引用文献	Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe, 29, 2021

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