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7KS9

Cryo-EM structure of prefusion SARS-CoV-2 spike glycoprotein in complex with 910-30 Fab

Summary for 7KS9
Entry DOI10.2210/pdb7ks9/pdb
EMDB information23016
Descriptor910-30 Fab light chain, 910-30 Fab heavy chain, Spike glycoprotein, ... (5 entities in total)
Functional Keywordsneutralizing antibody, fusion protein, spike glycoprotein, covid-19, rbd, viral protein, immune system, viral protein-immune system complex, viral protein/immune system
Biological sourceHomo sapiens
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Total number of polymer chains5
Total formula weight486963.44
Authors
Cerutti, G.,Shapiro, L. (deposition date: 2020-11-21, release date: 2021-02-10, Last modification date: 2022-11-09)
Primary citationBanach, B.B.,Cerutti, G.,Fahad, A.S.,Shen, C.H.,Oliveira De Souza, M.,Katsamba, P.S.,Tsybovsky, Y.,Wang, P.,Nair, M.S.,Huang, Y.,Francino-Urdaniz, I.M.,Steiner, P.J.,Gutierrez-Gonzalez, M.,Liu, L.,Lopez Acevedo, S.N.,Nazzari, A.F.,Wolfe, J.R.,Luo, Y.,Olia, A.S.,Teng, I.T.,Yu, J.,Zhou, T.,Reddem, E.R.,Bimela, J.,Pan, X.,Madan, B.,Laflin, A.D.,Nimrania, R.,Yuen, K.Y.,Whitehead, T.A.,Ho, D.D.,Kwong, P.D.,Shapiro, L.,DeKosky, B.J.
Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses.
Cell Rep, 37:109771-109771, 2021
Cited by
PubMed: 34587480
DOI: 10.1016/j.celrep.2021.109771
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.75 Å)
Structure validation

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