7LAA

Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1041

Summary for 7LAA

• Entry DOI: 10.2210/pdb7laa/pdb
• Related: 7LAB 7LCN 7LD1
• EMDB information: 23246
• Descriptor: Spike glycoprotein, DH1041 heavy chain, DH1041 light chain, ... (6 entities in total)
• Functional Keywords: rbd antibody, dh1041, sars, covid-19, sars-cov-2 2p s ectodomain, viral protein, immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 5
• Total formula weight: 431493.97

Authors

Manne, K.,Acharya, P. (deposition date: 2021-01-06, release date: 2021-03-17, Last modification date: 2021-08-18)

• Primary citation: Li, D.,Edwards, R.J.,Manne, K.,Martinez, D.R.,Schafer, A.,Alam, S.M.,Wiehe, K.,Lu, X.,Parks, R.,Sutherland, L.L.,Oguin 3rd, T.H.,McDanal, C.,Perez, L.G.,Mansouri, K.,Gobeil, S.M.C.,Janowska, K.,Stalls, V.,Kopp, M.,Cai, F.,Lee, E.,Foulger, A.,Hernandez, G.E.,Sanzone, A.,Tilahun, K.,Jiang, C.,Tse, L.V.,Bock, K.W.,Minai, M.,Nagata, B.M.,Cronin, K.,Gee-Lai, V.,Deyton, M.,Barr, M.,Von Holle, T.,Macintyre, A.N.,Stover, E.,Feldman, J.,Hauser, B.M.,Caradonna, T.M.,Scobey, T.D.,Rountree, W.,Wang, Y.,Moody, M.A.,Cain, D.W.,DeMarco, C.T.,Denny, T.N.,Woods, C.W.,Petzold, E.W.,Schmidt, A.G.,Teng, I.T.,Zhou, T.,Kwong, P.D.,Mascola, J.R.,Graham, B.S.,Moore, I.N.,Seder, R.,Andersen, H.,Lewis, M.G.,Montefiori, D.C.,Sempowski, G.D.,Baric, R.S.,Acharya, P.,Haynes, B.F.,Saunders, K.O.; In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.; Cell, 184:4203-, 2021; PubMed: 34242577; DOI: 10.1016/j.cell.2021.06.021

Experimental method

ELECTRON MICROSCOPY (3.42 Å)