7LS9

Cryo-EM structure of neutralizing antibody 1-57 in complex with prefusion SARS-CoV-2 spike glycoprotein

Summary for 7LS9

Entry DOI	10.2210/pdb7ls9/pdb
EMDB information	23506
Descriptor	Spike glycoprotein, 1-57 Fab heavy chain, 1-57 Fab light chain, ... (6 entities in total)
Functional Keywords	neutralizing antibody, fusion protein, spike glycoprotein, covid-19, rbd, rbd-directed antibody, 1-57, viral protein, immune system, viral protein-immune system complex, viral protein/immune system
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More
Total number of polymer chains	9
Total formula weight	592526.31
Authors	Cerutti, G.,Shapiro, L. (deposition date: 2021-02-17, release date: 2021-03-17, Last modification date: 2021-09-29)
Primary citation	Cerutti, G.,Rapp, M.,Guo, Y.,Bahna, F.,Bimela, J.,Reddem, E.R.,Yu, J.,Wang, P.,Liu, L.,Huang, Y.,Ho, D.D.,Kwong, P.D.,Sheng, Z.,Shapiro, L. Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies. Structure, 29:655-663.e4, 2021 Cited by PubMed: 34111408 DOI: 10.1016/j.str.2021.05.014 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.42 Å)

Structure validation