7LCN

Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1050.1

Summary for 7LCN

• Entry DOI: 10.2210/pdb7lcn/pdb
• Related: 7LAA 7LAB
• EMDB information: 23277
• Descriptor: Spike glycoprotein, DH1050.1 heavy chain, DH1050.1 light chain, ... (5 entities in total)
• Functional Keywords: rbd antibody, dh1050.1, sars, covid-19, sars-cov-2 2p s ectodomain, viral protein, immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); More
• Total number of polymer chains: 9
• Total formula weight: 525709.44

Authors

Manne, K.,Acharya, P. (deposition date: 2021-01-11, release date: 2021-01-27, Last modification date: 2021-08-18)

• Primary citation: Li, D.,Edwards, R.J.,Manne, K.,Martinez, D.R.,Schafer, A.,Alam, S.M.,Wiehe, K.,Lu, X.,Parks, R.,Sutherland, L.L.,Oguin 3rd, T.H.,McDanal, C.,Perez, L.G.,Mansouri, K.,Gobeil, S.M.C.,Janowska, K.,Stalls, V.,Kopp, M.,Cai, F.,Lee, E.,Foulger, A.,Hernandez, G.E.,Sanzone, A.,Tilahun, K.,Jiang, C.,Tse, L.V.,Bock, K.W.,Minai, M.,Nagata, B.M.,Cronin, K.,Gee-Lai, V.,Deyton, M.,Barr, M.,Von Holle, T.,Macintyre, A.N.,Stover, E.,Feldman, J.,Hauser, B.M.,Caradonna, T.M.,Scobey, T.D.,Rountree, W.,Wang, Y.,Moody, M.A.,Cain, D.W.,DeMarco, C.T.,Denny, T.N.,Woods, C.W.,Petzold, E.W.,Schmidt, A.G.,Teng, I.T.,Zhou, T.,Kwong, P.D.,Mascola, J.R.,Graham, B.S.,Moore, I.N.,Seder, R.,Andersen, H.,Lewis, M.G.,Montefiori, D.C.,Sempowski, G.D.,Baric, R.S.,Acharya, P.,Haynes, B.F.,Saunders, K.O.; In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.; Cell, 184:4203-, 2021; PubMed: 34242577; DOI: 10.1016/j.cell.2021.06.021

Experimental method

ELECTRON MICROSCOPY (3.35 Å)