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2O5Z
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Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab 5-beta-androstane-3,17-dione complex
分子名称: 5-BETA-ANDROSTANE-3,17-DIONE, SULFATE ION, chimeric antibody Fab 1E9-DB3
著者Verdino, P, Wilson, I.A.
登録日2006-12-06
公開日2007-12-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2OJZ
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Anti-DNA antibody ED10
分子名称: Fab ED10 heavy chain, Fab ED10 light chain
著者Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
登録日2007-01-15
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
2O5X
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Crystal structure of 1E9 LeuH47Trp/ArgH100Trp, an engineered Diels-Alderase Fab with nM steroid-binding affinity
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, chimeric antibody Fab 1E9-DB3
著者Verdino, P, Wilson, I.A.
登録日2006-12-06
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
6NHQ
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Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA2 I45M mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2018-12-23
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Different genetic barriers for resistance to HA stem antibodies in influenza H3 and H1 viruses.
Science, 368, 2020
6NCP
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BU of 6ncp by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody ACS202
分子名称: ACS202 Fab heavy chain, ACS202 Fab light chain, GLYCINE, ...
著者Yuan, M, Wilson, I.A.
登録日2018-12-11
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies.
Cell Host Microbe, 25, 2019
6O30
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Lipid A transporter MsbA from Salmonella typhimurium
分子名称: Lipid A export ATP-binding/permease protein MsbA
著者Padayatti, P.S, Zhang, Q, Wilson, I.A, Lee, S.C, Stanfield, R.L.
登録日2019-02-25
公開日2019-06-12
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.47 Å)
主引用文献Structural Insights into the Lipid A Transport Pathway in MsbA.
Structure, 27, 2019
6O3D
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BU of 6o3d by Molmil
Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.
分子名称: GLYCEROL, PGZL1 FAB HEAVY CHAIN, PGZL1 FAB LIGHT CHAIN, ...
著者Irimia, A, Wilson, I.A.
登録日2019-02-26
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O3J
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Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41) and phosphatidic acid (06:0 PA)
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, (4S)-2-METHYL-2,4-PENTANEDIOL, MPER peptide, ...
著者Irimia, A, Wilson, I.A.
登録日2019-02-26
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.416 Å)
主引用文献An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6NSC
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Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin G186V/L194P mutant apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wu, N.C, Wilson, I.A.
登録日2019-01-24
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility.
Cell Host Microbe, 25, 2019
6NS9
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BU of 6ns9 by Molmil
Crystal structure of the IVR-165 (H3N2) influenza virus hemagglutinin apo form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Wu, N.C, Wilson, I.A.
登録日2019-01-24
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility.
Cell Host Microbe, 25, 2019
6NSF
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Crystal structure of the A/Brisbane/10/2007 (H3N2) influenza virus hemagglutinin G186V/L194P mutant in complex with 3'-SLNLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wu, N.C, Wilson, I.A.
登録日2019-01-24
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility.
Cell Host Microbe, 25, 2019
2OQJ
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BU of 2oqj by Molmil
Crystal structure analysis of Fab 2G12 in complex with peptide 2G12.1
分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, peptide 2G12.1 (ACPPSHVLDMRSGTCLAAEGK)
著者Calarese, D.A, Stanfield, R.L, Menendez, A, Scott, J.K, Wilson, I.A.
登録日2007-01-31
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.
Faseb J., 22, 2008
6O3K
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BU of 6o3k by Molmil
Crystal structure of the unbound Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3
分子名称: GLYCEROL, PGZL1.H4K3 heavy chain, PGZL1.H4K3 light chain, ...
著者Irimia, A, Wilson, I.A.
登録日2019-02-26
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
2OP4
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Crystal Structure of Quorum-Quenching Antibody 1G9
分子名称: 1,2-ETHANEDIOL, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
著者Kirchdoerfer, R.N, Debler, E.W, Wilson, I.A.
登録日2007-01-26
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
6O3U
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BU of 6o3u by Molmil
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with 06:0 PA
分子名称: (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, GLYCEROL, PGZL1.H4K3 heavy chain, ...
著者Irimia, A, Wilson, I.A.
登録日2019-02-27
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.105 Å)
主引用文献An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6O3L
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BU of 6o3l by Molmil
Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41).
分子名称: GLYCEROL, MPER peptide, region 671-683 of HIV-1 gp41, ...
著者Irimia, A, Wilson, I.A.
登録日2019-02-26
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
2OK0
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Fab ED10-DNA complex
分子名称: 5'-D(*TP*C)-3', Fab ED10 heavy chain, Fab ED10 light chain
著者Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
登録日2007-01-15
公開日2007-06-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
6O41
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BU of 6o41 by Molmil
Crystal structure of the unbound PGZL1 germline Fab fragment (PGZL1_gVmDmJ)
分子名称: GLYCEROL, Immunoglobulin G-binding protein G (DOMAIN III), germline PGZL1_gVmDmJ heavy chain, ...
著者Irimia, A, Wilson, I.A.
登録日2019-02-27
公開日2019-12-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.465 Å)
主引用文献An MPER antibody neutralizes HIV-1 using germline features shared among donors.
Nat Commun, 10, 2019
6OO0
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Crystal structure of bovine Fab NC-Cow1
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, NC-Cow1 heavy chain, NC-Cow1 light chain
著者Stanfield, R.L, Wilson, I.A.
登録日2019-04-22
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020
6OPA
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BU of 6opa by Molmil
Crystal structure of bovine Fab NC-Cow1 in complex with HIV-1 BG505 SOSIP.664, and human Fabs 35022 and PGT128
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Stanfield, R.L, Wilson, I.A.
登録日2019-04-24
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (4.084 Å)
主引用文献Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020
2PRT
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BU of 2prt by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
分子名称: DNA (5'-D(*CP*AP*GP*AP*CP*GP*CP*CP*CP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*GP*GP*GP*CP*GP*TP*CP*TP*G)-3'), Wilms tumor 1, ...
著者Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2007-05-04
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2NTF
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BU of 2ntf by Molmil
Crystal Structure of a Quorum-Quenching Antibody in Complex with an N-Acyl-L-Homoserine Lactone Analog
分子名称: 3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
著者Debler, E.W, Wilson, I.A.
登録日2006-11-07
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
2Q7Y
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Structure of the endogenous iNKT cell ligand iGb3 bound to mCD1d
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Zajonc, D.M, Wilson, I.A, Teyton, L.
登録日2007-06-07
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Valpha14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids.
J.Mol.Biol., 377, 2008
2QGE
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Human transthyretin (TTR) complexed with 2-(3,5-Dimethylphenyl)benzoxazole
分子名称: 2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2007-06-28
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
2QGB
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Human transthyretin (TTR) in Apo-form
分子名称: Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2007-06-28
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008

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