1ERN
NATIVE STRUCTURE OF THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP]
Summary for 1ERN
Entry DOI | 10.2210/pdb1ern/pdb |
Descriptor | PROTEIN (ERYTHROPOIETIN RECEPTOR) (2 entities in total) |
Functional Keywords | erythropoietin receptor, signal transduction, cytokine receptor class 1, cytokine |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Single-pass type I membrane protein. Isoform EPOR-S: Secreted: P19235 |
Total number of polymer chains | 2 |
Total formula weight | 47023.32 |
Authors | Livnah, O.,Stura, E.A.,Wilson, I.A. (deposition date: 1999-01-11, release date: 2000-01-07, Last modification date: 2023-08-09) |
Primary citation | Livnah, O.,Stura, E.A.,Middleton, S.A.,Johnson, D.L.,Jolliffe, L.K.,Wilson, I.A. Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation. Science, 283:987-990, 1999 Cited by PubMed: 9974392DOI: 10.1126/science.283.5404.987 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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