7LK9

Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 HC + COVD21-C8 LC

Summary for 7LK9

• Entry DOI: 10.2210/pdb7lk9/pdb
• Descriptor: COV107-23 heavy chain, COVD21-C8 light chain (2 entities in total)
• Functional Keywords: coronavirus, covid-19, sars-cov-2, antibody, fab, receptor binding domain, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 186775.92

Authors

Yuan, M.,Zhu, X.,Wilson, I.A.,Wu, N.C. (deposition date: 2021-02-01, release date: 2021-02-17, Last modification date: 2023-10-18)

• Primary citation: Tan, T.J.C.,Yuan, M.,Kuzelka, K.,Padron, G.C.,Beal, J.R.,Chen, X.,Wang, Y.,Rivera-Cardona, J.,Zhu, X.,Stadtmueller, B.M.,Brooke, C.B.,Wilson, I.A.,Wu, N.C.; Sequence signatures of two public antibody clonotypes that bind SARS-CoV-2 receptor binding domain.; Nat Commun, 12:3815-3815, 2021; PubMed: 34155209; DOI: 10.1038/s41467-021-24123-7

Experimental method

X-RAY DIFFRACTION (3.4 Å)