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7NQB
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BU of 7nqb by Molmil
X.ray structure of the oxaliplatin/beta-lactoglobulin adduct
分子名称: Beta-lactoglobulin, PLATINUM (II) ION
著者Merlino, A, Loreto, D, Ferraro, G.
登録日2021-03-01
公開日2022-03-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Protein-Based Delivery Systems for Anticancer Metallodrugs: Structure and Biological Activity of the Oxaliplatin/ beta-Lactoglobulin Adduct.
Pharmaceuticals, 15, 2022
6RJV
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BU of 6rjv by Molmil
The X-ray structure of the Gold/Serum Albumin adduct obtained upon reaction of the protein with AuL12, a gold(III) dithiocarbamate complex
分子名称: GOLD ION, MAGNESIUM ION, Serum albumin
著者Merlino, A, Giorgio, A, Ferraro, G.
登録日2019-04-29
公開日2019-08-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.21 Å)
主引用文献Structural Characterization of a Gold/Serum Albumin Complex.
Inorg.Chem., 58, 2019
7OR6
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BU of 7or6 by Molmil
The crystal structure of the domain-swapped dimer of onconase
分子名称: Protein P-30
著者Merlino, A, Loreto, D.
登録日2021-06-04
公開日2021-10-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme.
Int.J.Biol.Macromol., 191, 2021
7ORD
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BU of 7ord by Molmil
The crystal structure of the domain-swapped dimer of onconase (2)
分子名称: ACETATE ION, Protein P-30, SULFATE ION
著者Merlino, A, Loreto, D.
登録日2021-06-05
公開日2021-10-06
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献The crystal structure of the domain-swapped dimer of onconase highlights some catalytic and antitumor activity features of the enzyme.
Int.J.Biol.Macromol., 191, 2021
7R1Q
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BU of 7r1q by Molmil
X-ray structure of the adduct formed upon reaction of the gold(I) N-heterocyclic carbene complex Au2 with lysozyme
分子名称: DIMETHYL SULFOXIDE, GOLD ION, Lysozyme
著者Merlino, A, Ferraro, G.
登録日2022-02-03
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Halo complexes of gold(I) containing glycoconjugate carbene ligands: synthesis, characterization, cytotoxicity and interaction with proteins and DNA model systems.
Dalton Trans, 51, 2022
7R1P
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BU of 7r1p by Molmil
X-ray structure of the adduct formed upon reaction of the gold(I) N-heterocyclic carbene complex Au1 with RNase A
分子名称: GOLD ION, Ribonuclease pancreatic, SULFATE ION
著者Merlino, A, Ferraro, G.
登録日2022-02-03
公開日2022-07-13
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Halo complexes of gold(I) containing glycoconjugate carbene ligands: synthesis, characterization, cytotoxicity and interaction with proteins and DNA model systems.
Dalton Trans, 51, 2022
6XW0
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BU of 6xw0 by Molmil
X-ray structure obtained upon reaction of dirhodium tetraacetate with RNase A (low resolution)
分子名称: ACETATE ION, RHODIUM(III) ION, Ribonuclease pancreatic
著者Merlino, A, Ferraro, G.
登録日2020-01-22
公開日2020-02-19
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Protein interactions of dirhodium tetraacetate: a structural study.
Dalton Trans, 49, 2020
6XVX
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BU of 6xvx by Molmil
X-ray structure obtained upon reaction of dirhodium tetraacetate with RNase A (high resolution)
分子名称: ACETATE ION, RHODIUM(III) ION, Ribonuclease pancreatic
著者Merlino, A, Ferraro, G.
登録日2020-01-22
公開日2020-02-19
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Protein interactions of dirhodium tetraacetate: a structural study.
Dalton Trans, 49, 2020
4IRO
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BU of 4iro by Molmil
Crystal structure of T-state carbonmonoxy hemoglobin from Trematomus bernacchii at pH 8.4
分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ...
著者Merlino, A, Balsamo, A, Mazzarella, L, Vergara, A.
登録日2013-01-15
公開日2013-02-20
最終更新日2013-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Role of tertiary structures on the Root effect in fish hemoglobins.
Biochim.Biophys.Acta, 1834, 2013
5E5E
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BU of 5e5e by Molmil
X-ray structure of the adduct formed in the reaction between RNase A and a neutral organometallic derivative [Pt(pbi)(Me)(DMSO)], pbi=2-(2'-pyridil)benzimidazole (compound 3)
分子名称: DIMETHYL SULFOXIDE, PLATINUM (II) ION, Ribonuclease pancreatic
著者Merlino, A.
登録日2015-10-08
公開日2015-12-09
最終更新日2016-01-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Cytotoxic properties of a new organometallic platinum(ii) complex and its gold(i) heterobimetallic derivatives.
Dalton Trans, 45, 2015
5E5F
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BU of 5e5f by Molmil
X-ray structure of the complex between RNase A and compound 4-PF6 ([(PPh3)Au(mi-pbi)Pt(Me)(DMSO)][PF6]), the heterobimetallic derivative obtained in the reaction between the organometallic compound [Pt(pbi)(Me)(DMSO)], pbi=2-(2'-pyridil)benzimidazole (compound 3) and the gold(I) compound [Au(Ph3P)][PF6]
分子名称: ACETATE ION, GOLD ION, Ribonuclease pancreatic, ...
著者Merlino, A.
登録日2015-10-08
公開日2015-12-09
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Cytotoxic properties of a new organometallic platinum(ii) complex and its gold(i) heterobimetallic derivatives.
Dalton Trans, 45, 2015
6QEA
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BU of 6qea by Molmil
The X-ray structure of the adduct formed in the reaction between hen egg white lysozyme and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands
分子名称: DIMETHYL SULFOXIDE, Lysozyme C, NITRATE ION, ...
著者Merlino, A, Ferraro, G.
登録日2019-01-07
公開日2019-03-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Reaction with Proteins of a Five-Coordinate Platinum(II) Compound.
Int J Mol Sci, 20, 2019
8B4N
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BU of 8b4n by Molmil
X-ray structure of phycoerythrin from Porphyridium cruentum
分子名称: B-phycoerythrin alpha chain, B-phycoerythrin beta chain, PHYCOERYTHROBILIN, ...
著者Merlino, A, Ferraro, G.
登録日2022-09-20
公開日2023-02-08
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inside out Porphyridium cruentum : Beyond the Conventional Biorefinery Concept.
Acs Sustain Chem Eng, 11, 2023
6QE9
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BU of 6qe9 by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and complex I, a pentacoordinate Pt(II) compound containing 2,9-dimethyl-1,10-phenanthroline, dimethylfumarate, methyl and iodine as ligands
分子名称: Ribonuclease pancreatic, SULFATE ION, pentacoordinate Pt(II) compound
著者Merlino, A, Ferraro, G.
登録日2019-01-07
公開日2019-02-27
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Reaction with Proteins of a Five-Coordinate Platinum(II) Compound.
Int J Mol Sci, 20, 2019
6F60
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BU of 6f60 by Molmil
The x-ray structure of bovine pancreatic ribonuclease in complex with a five-coordinate platinum(II) compound containing a sugar ligand
分子名称: Ribonuclease pancreatic, SULFATE ION, five-coordinate platinum(II) compound
著者Merlino, A, Ferraro, G.
登録日2017-12-04
公開日2018-04-25
実験手法X-RAY DIFFRACTION (1.14 Å)
主引用文献Five-Coordinate Platinum(II) Compounds Containing Sugar Ligands: Synthesis, Characterization, Cytotoxic Activity, and Interaction with Biological Macromolecules.
Inorg Chem, 57, 2018
4Z41
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BU of 4z41 by Molmil
X-ray structure of the adduct formed in the reaction between lysozyme and a platinum(II) Compound with a S,O Bidentate Ligand (9a=Chloro-(1-(3'-hydroxy)-3-(methylthio)-3-thioxo-prop-1-en-1-olate-O,S)-(dimethylsulfoxide-S)-platinum(II))
分子名称: 1,2-ETHANEDIOL, 3-[2-chloranyl-2-[dimethyl(oxidanyl)-{4}-sulfanyl]-4-ethylsulfanyl-1-oxa-3{3}-thia-2{4}-platinacyclohexa-3,5-dien-6-yl]phenol, DIMETHYL SULFOXIDE, ...
著者Merlino, A.
登録日2015-04-01
公開日2015-09-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Platinum(II) Complexes with O,S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding.
Inorg.Chem., 54, 2015
4Z3M
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BU of 4z3m by Molmil
X-ray structure of the adduct formed in the reaction between lysozyme and a platinum(II) Complex with S,O Bidentate Ligands (9b)
分子名称: 1,2-ETHANEDIOL, 3-[2-chloranyl-2-[dimethyl(oxidanyl)-{4}-sulfanyl]-4-ethylsulfanyl-1-oxa-3{3}-thia-2{4}-platinacyclohexa-3,5-dien-6-yl]phenol, DIMETHYL SULFOXIDE, ...
著者Merlino, A.
登録日2015-03-31
公開日2015-09-02
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Platinum(II) Complexes with O,S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding.
Inorg.Chem., 54, 2015
4Z46
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BU of 4z46 by Molmil
X-ray structure of the bis-platinum lysozyme adduct formed in the reaction between the protein and the two drugs Cisplatin and Oxaliplatin
分子名称: 1,2-ETHANEDIOL, CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II), Cisplatin, ...
著者Merlino, A.
登録日2015-04-01
公開日2015-05-27
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Oxaliplatin vs. cisplatin: competition experiments on their binding to lysozyme.
Dalton Trans, 44, 2015
4ZFP
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BU of 4zfp by Molmil
A new crystal structure for the adduct formed in the reaction between AuSac2, a cytotoxic homoleptic gold(I) compound with the saccharinate ligand, and the model protein hen egg white lysozyme
分子名称: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ...
著者Merlino, A.
登録日2015-04-21
公開日2015-06-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural evidences for a secondary gold binding site in the hydrophobic box of lysozyme.
Biometals, 28, 2015
4S0Q
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BU of 4s0q by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and carboplatin
分子名称: Ribonuclease pancreatic, carboplatin
著者Merlino, A.
登録日2015-01-04
公開日2015-11-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts.
J.Inorg.Biochem., 153, 2015
4RSZ
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BU of 4rsz by Molmil
The X-ray structure of the Primary Adduct formed in the Reaction between Cisplatin and Cytochrome c
分子名称: Cisplatin, Cytochrome c, HEME C, ...
著者Merlino, A.
登録日2014-11-12
公開日2015-01-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献The X-ray structure of the primary adducts formed in the reaction between cisplatin and cytochrome c.
Chem.Commun.(Camb.), 51, 2015
4ZEE
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BU of 4zee by Molmil
X-ray structure of the bis-platinum lysozyme adduct formed in the reaction between the protein and the two drugs Cisplatin and Oxaliplatin (preparation 2)
分子名称: 1,2-ETHANEDIOL, CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II), Cisplatin, ...
著者Merlino, A.
登録日2015-04-20
公開日2015-05-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Oxaliplatin vs. cisplatin: competition experiments on their binding to lysozyme.
Dalton Trans, 44, 2015
4S18
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BU of 4s18 by Molmil
The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and oxaliplatin
分子名称: CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II), Ribonuclease pancreatic
著者Merlino, A.
登録日2015-01-09
公開日2015-11-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts.
J.Inorg.Biochem., 153, 2015
4S1Y
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BU of 4s1y by Molmil
X-ray structure of human serum albumin complexed with cisplatin
分子名称: Cisplatin, Serum albumin
著者Merlino, A.
登録日2015-01-16
公開日2015-04-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Cisplatin binding to human serum albumin: a structural study.
Chem.Commun.(Camb.), 51, 2015
4L2C
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BU of 4l2c by Molmil
X-ray structure of the C57R mutant of the iron superoxide dismutase from Pseudoalteromonas haloplanktis (crystal form I)
分子名称: FE (III) ION, Superoxide dismutase [Fe], alpha-D-glucopyranose-(1-1)-alpha-D-glucopyranose
著者Russo Krauss, I, Merlino, A, Sica, F.
登録日2013-06-04
公開日2014-02-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability.
Biochim.Biophys.Acta, 1844, 2014

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