6F60

The x-ray structure of bovine pancreatic ribonuclease in complex with a five-coordinate platinum(II) compound containing a sugar ligand

Summary for 6F60

• Entry DOI: 10.2210/pdb6f60/pdb
• Descriptor: Ribonuclease pancreatic, SULFATE ION, five-coordinate platinum(II) compound, ... (5 entities in total)
• Functional Keywords: ribonuclease, platinum(ii) compound, five-coordinate, sugar ligand, cytotoxicity, hydrolase
• Biological source: Bos taurus (Bovine)
• Cellular location: Secreted: P61823
• Total number of polymer chains: 2
• Total formula weight: 28683.76

Authors

Merlino, A.,Ferraro, G. (deposition date: 2017-12-04, release date: 2018-04-25)

• Primary citation: Cucciolito, M.E.,D'Amora, A.,De Feo, G.,Ferraro, G.,Giorgio, A.,Petruk, G.,Monti, D.M.,Merlino, A.,Ruffo, F.; Five-Coordinate Platinum(II) Compounds Containing Sugar Ligands: Synthesis, Characterization, Cytotoxic Activity, and Interaction with Biological Macromolecules.; Inorg Chem, 57:3133-3143, 2018; PubMed: 29509011; DOI: 10.1021/acs.inorgchem.7b03118

Experimental method

X-RAY DIFFRACTION (1.14 Å)