4S0Q

The X-ray structure of the adduct formed in the reaction between bovine pancreatic ribonuclease and carboplatin

Summary for 4S0Q

Entry DOI	10.2210/pdb4s0q/pdb
Descriptor	Ribonuclease pancreatic, carboplatin (3 entities in total)
Functional Keywords	ribonuclease, rna cleavage, hydrolase-rna complex, hydrolase/rna
Biological source	Bos taurus (bovine,cow,domestic cattle,domestic cow)
Cellular location	Secreted: P61823
Total number of polymer chains	2
Total formula weight	28159.15
Authors	Merlino, A. (deposition date: 2015-01-04, release date: 2015-11-18, Last modification date: 2023-09-20)
Primary citation	Messori, L.,Marzo, T.,Merlino, A. Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts. J.Inorg.Biochem., 153:136-142, 2015 Cited by PubMed: 26239545 DOI: 10.1016/j.jinorgbio.2015.07.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.09 Å)

Structure validation